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학술저널
저자정보
Kim, Minjung (Department of Internal Medicine, Kyungpook National University School of Medicine) Cha, Seung-Ick (Department of Internal Medicine, Kyungpook National University School of Medicine) Seo, Hyewon (Department of Internal Medicine, Kyungpook National University School of Medicine) Shin, Kyung-Min (Department of Radiology, Kyungpook National University School of Medicine) Lim, Jae-Kwang (Department of Radiology, Kyungpook National University School of Medicine) Kim, Hyera (Department of Internal Medicine, Kyungpook National University School of Medicine) Yoo, Seung-Soo (Department of Internal Medicine, Kyungpook National University School of Medicine) Lee, Jaehee (Department of Internal Medicine, Kyungpook National University School of Medicine) Lee, Shin-Yup (Department of Internal Medicine, Kyungpook National University School of Medicine) Kim, Chang-Ho (Department of Internal Medicine, Kyungpook National University School of Medicine) Park, Jae-Yong (Department of Internal Medicine, Kyungpook National University School of Medicine)
저널정보
대한결핵 및 호흡기학회 Tuberculosis and Respiratory Diseases 결핵 및 호흡기 질환 제78권 제3호
발행연도
2015.1
수록면
190 - 195 (6page)

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Background: Although organizing pneumonia (OP) responds well to corticosteroid therapy, relapse is common during dose reduction or follow-up. Predictors of relapse in OP patients remain to be established. The aim of the present study was to identify factors related to relapse in OP patients. Methods: This study was retrospectively performed in a tertiary referral center. Of 66 OP patients who were improved with or without treatment, 20 (30%) experienced relapse. The clinical and radiologic parameters in the relapse patient group (n=20) were compared to that in the non-relapse group (n=46). Results: Multivariate analysis demonstrated that percent predicted forced vital capacity (FVC), $PaO_2/FiO_2$, and serum protein level were significant predictors of relapse in OP patients (odds ratio [OR], 0.82; 95% confidence interval [CI], 0.70-0.97; p=0.018; OR, 1.02; 95% CI, 1.00-1.04; p=0.042; and OR, 0.06; 95% CI, 0.01-0.87; p=0.039, respectively). Conclusion: This study shows that FVC, $PaO_2/FiO_2$ and serum protein level at presentation can significantly predict relapse in OP patients.

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