지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 37 - 42 (6page)
이용수
초록· 키워드
오류제보하기
Hemolytic uremic syndrome (HUS) is often encountered in children with acute kidney injury. Besides the well-known shiga toxin-producing Escherichia coli-associated HUS, atypical HUS (aHUS) caused by genetic complement dysregulation has been studied recently. aHUS is a rare, chronic, and devastating disorder that progressively damages systemic organs, resulting in stroke, end-stage renal disease, and death. The traditional treatment for aHUS is mainly plasmapheresis or plasma infusion; however, many children with aHUS will progress to chronic kidney disease despite plasma therapy. Eculizumab is a newly developed biologic that blocks the terminal complement pathway and has been successfully used in the treatment of aHUS. Currently, several guidelines for aHUS, including the Korean guideline, recommend eculizumab as the first-line therapy in children with aHUS. Moreover, life-long eculizumab therapy is generally recommended. Further studies on discontinuation of eculizumab are needed.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Rapid Resolution of Atypical Hemolytic Uremic Syndrome by Eculizumab Treatment
Childhood Kidney Diseases
2020 .01
-
Recurrent hemolytic uremic syndrome caused by DGKE gene mutation: a case report
Childhood Kidney Diseases
2022 .06
-
Eculizumab 치료로 호전된 비정형 용혈요독증후군 1예
대한내과학회지
2020 .04
-
Atypical Hemolytic Uremic Syndrome in a 13-year-old Lao Girl: A Case Report
Childhood Kidney Diseases
2019 .01
-
Case Report of Pregnancy Induced Atypical Hemolytic-uremic Syndrome
Perinatology
2021 .01
-
The first successful eculizumab rescue therapy of a kidney transplant recipient with atypical hemolytic uremic syndrome in South Korea: a case report
Clinical Transplantation and Research
2023 .03
-
Prognostic utility of ADAMTS13 activity for the atypical hemolytic uremic syndrome (aHUS) and comparison of complement serology between aHUS and thrombotic thrombocytopenic purpura
Blood Research
2019 .01
-
Concurrent cytomegalovirus enteritis and atypical hemolytic uremic syndrome with gastrointestinal tract involvement: a case report
Clinical Transplantation and Research
2021 .12
-
A case of atypical hemolytic uremic syndrome associated with the c.1273C＞T mutation in the complement C3 gene
Blood Research
2016 .01
-
Eculizumab as rescue therapy in a kidney transplant recipient with atypical hemolytic uremic syndrome: a case report
Clinical Transplantation and Research
2022 .12
-
A new pathological perspective on thrombotic microangiopathy
Kidney Research and Clinical Practice
2022 .09
-
A Case of Streptococcus pneumoniae associated Hemolytic Uremic Syndrome with DIC
Childhood Kidney Diseases
2015 .01
-
A Case of Microangiopathic Hemolytic Anemia after Myxoma Excision and Mitral Valve Repair Presenting as Hemolytic Uremic Syndrome
Journal of Cardiovascular Imaging
2016 .01
-
Hemolytic uremic syndrome caused by Escherichia fergusonii infection
Kidney Research and Clinical Practice
2019 .01
-
혈전미세혈관병증의 감별 진단과 치료
대한내과학회지
2019 .02
-
Recombinant Human Erythropoietin Therapy for a Jehovah's Witness Child With Severe Anemia due to Hemolytic-Uremic Syndrome
Clinical and Experimental Pediatrics
2016 .01
-
Characteristics and management of thrombotic microangiopathy in kidney transplantation
Clinical Transplantation and Research
2023 .03
-
Uremic pruritus: pathophysiology, clinical presentation, and treatments
Kidney Research and Clinical Practice
2023 .01
-
The “Collar Tab Sign”–An Atypical Mri Feature in Uremic Encephalopathy
Journal of Clinical Neurology
2023 .01
-
A 22-month-old Boy with Acute Glomerulonephritis Coexistent with Hemolytic Anemia and Idiopathic Thrombocytopenia
Childhood Kidney Diseases
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0