지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Objectives Local gyrification reflects the early neural development of cortical connectivity, and is regarded as a potential neural endophenotype in psychiatric disorders. Several studies have suggested altered local gyrification in patients with bipolar I disorder (BD-I). The purpose of the present study was to investigate the alterations in the cortical gyrification of whole brain cortices in patients with BD-I. Methods Twenty-two patients with BD-I and age and sex-matched 22 healthy controls (HC) were included in this study. All participants underwent T1-weighted structural magnetic resonance imaging (MRI). The local gyrification index (LGI) of 66 cortical regions were analyzed using the FreeSurfer (Athinoula A. Martinos Center for Biomedical Imaging). One-way analysis of covariance (ANCOVA) was used to analyze the difference of LGI values between two groups adjusting for age and sex as covariates. Results The patients with BD-I showed significant hypogyria in the left pars opercularis (uncorrected-p = 0.049), the left rostral anterior cingulate gyrus (uncorrected-p = 0.012), the left caudal anterior cingulate gyrus (uncorrected-p = 0.033). However, these findings were not significant after applying the multiple comparison correction. Severity or duration of illness were not significantly correlated with LGI in the patients with BD-I. Conclusions Our results of lower LGI in the anterior cingulate cortex and the ventrolateral prefrontal cortex in the BD-I group implicate that altered cortical gyrification in neural circuits involved in emotion-processing may contribute to pathophysiology of BD-I.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Decreased Cortical Thickness and Local Gyrification in Individuals with Subjective Cognitive Impairment
Clinical Psychopharmacology and Neuroscience
2021 .11
-
Cortical Thickness and Surface Area Abnormalities in Bipolar I and II Disorders
PSYCHIATRY INVESTIGATION
2021 .09
-
Significant Shortening of Leukocyte Telomere Length in Korean Patients with Bipolar Disorder 1
Clinical Psychopharmacology and Neuroscience
2021 .08
-
Clinical Characteristics of Pediatric Bipolar Disorder by Subtype in a Korean Inpatient Sample
소아청소년정신의학
2015 .12
-
유럽인 자료로 산출된 양극성 장애 다유전자 위험 점수의 한국인 양극성 장애 환자에의 적용
신경정신의학
2021 .08
-
Epidemiologic and Etiological Features of Korean Patients With Behcet’s Disease
대한류마티스학회지
2021 .10
-
Genetic Association of the PERIOD3 (Per3) Clock Gene with Bipolar Disorder
PSYCHIATRY INVESTIGATION
2017 .01
-
Higher Prevalence of Metabolic Syndrome in Child-adolescent Patients with Bipolar Disorder
Clinical Psychopharmacology and Neuroscience
2020 .01
-
Similarities of Aspects of Biological Rhythms between Major Depression and Bipolar II Disorder Compared to Bipolar I Disorder: A Finding from the Early-Onset Mood Disorder Cohort
PSYCHIATRY INVESTIGATION
2019 .01
-
Carpal Tunnel Syndrome in Behçet’s Disease
Yonsei Medical Journal
2015 .01
-
Is There a Correlation Between Behçet Disease and Lower Urinary Tract Symptoms?
International Neurourology Journal
2020 .01
-
Comparison of Serum Uric Acid in Major Depressive Disorder and Bipolar Disorder: a Retrospective Chart Review Study
Journal of Korean Medical Science
2020 .01
-
Measurement of Contrast Sensitivity in Patients with Behçet’s Disease without Ocular Involvement
Korean Journal of Ophthalmology
2019 .01
-
조현병과 제1형 양극성장애의 진단 경계를 넘어선 공통적 후보유전자로서의CACNA1C 에 대한 단일염기다형성 연합 연구
대한조현병학회지
2018 .01
-
Cortical Volumetric Correlates of Childhood Trauma, Anxiety, and Impulsivity in Bipolar Disorder
PSYCHIATRY INVESTIGATION
2020 .01
-
Cancer Risk in Patients with Intestinal Behçet’s Disease: A Nationwide Population-Based Study
Gut and Liver
2018 .01
-
Association of Prefrontal Cortex Thinning with High Impulsivity in Healthy Adults
PSYCHIATRY INVESTIGATION
2021 .01
-
Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder
Clinical Psychopharmacology and Neuroscience
2018 .01
-
양극성 장애 환자에서 회복력과 관련있는 기질 및 성격
생물치료정신의학
2023 .10
-
Network Structures of Social Functioning Domains in Schizophrenia and Bipolar Disorder: A Preliminary Study
Clinical Psychopharmacology and Neuroscience
2020 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0