지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제18권 제4호
- 발행연도
- 2020.1
- 수록면
- 571 - 579 (9page)
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초록· 키워드
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Objective: This study used network analyses to examine network structures reflecting interactions between specific domains of social functioning in schizophrenia (SZ) and bipolar disorder (BD). Methods: We used the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) to assess six domains of social functioning (‘cognition’, ‘mobility’, ‘self-care’, ‘getting along’, ‘life activities’, and ‘participation’) in 143 patients with SZ, 81 patients with BD, and 106 healthy subjects. We constructed regularized partial correlation networks, estimated network centrality and edge strength, tested network stability, and compared SZ and BD network structures. Results: Patients with SZ showed a significantly higher level of functional disability than patients with BD. In the networks we constructed, ‘cognition’ was the most central domain of social functioning in both SZ and BD. The ‘cognition’ domain was primarily associated with the ‘getting along’ domain in the SZ network and the ‘life activities’ domain in the BD network. We found no significant group-level differences in network structures for SZ vs. BD. Conclusion: Our results suggest that cognition may play a pivotal role in social functioning in both SZ and BD. In addition, domains of social functioning in SZ and BD have similar network structures despite the higher level of disability in SZ compared to BD.
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참고문헌 (36)
참고문헌 신청
Simons CJP / 2018 / Correction : cognitive performance and long-term social functioning in psychotic disorder : a three-year follow-up study / PLoS One 13:e0208347
Lee RS / 2015 / Neuropsychological and functional outcomes in recent-onset major depression, bipolar disorder and schizophrenia-spectrum disorders : a longitudinal cohort study / Transl Psychiatry 5:e555
Harvey PD / 2010 / The course of neuropsychological performance and functional capacity in older patients with schizophrenia : influences of previous history of long-term institutional stay / Biol Psychiatry 67:933~939
Adarsh Tripathi / 2018 / Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies / Clinical Psychopharmacology and Neuroscience 16(1):7~17
Lieberman JA / 1999 / Is schizophrenia a neurodegenerative disorder? A clinical and neurobiological perspective / Biol Psychiatry 46:729~739
Lee RS / 2015 / Neuropsychological and functional outcomes in recent-onset major depression, bipolar disorder and schizophrenia-spectrum disorders : a longitudinal cohort study / Transl Psychiatry 5:e555
Harvey PD / 2010 / The course of neuropsychological performance and functional capacity in older patients with schizophrenia : influences of previous history of long-term institutional stay / Biol Psychiatry 67:933~939
Adarsh Tripathi / 2018 / Cognitive Deficits in Schizophrenia: Understanding the Biological Correlates and Remediation Strategies / Clinical Psychopharmacology and Neuroscience 16(1):7~17
Lieberman JA / 1999 / Is schizophrenia a neurodegenerative disorder? A clinical and neurobiological perspective / Biol Psychiatry 46:729~739
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