지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Quercetin is one of the bioflavonoid compounds and has multiple biological effects such as antioxidant and effective anti-inflammatory agent. Melanin has an important role in protecting human skin from the damaging effects of ultra-violet W) radiation. We studied the effect of quercetin on proliferation of B16/F10 melanoma cells. After 48h treatment of cells with quercetin, the cells exhibited a dose-dependent inhibition in their proliferation without apoptosis. Therefore, the decrease in cell numbers may be due to cell growth arrest, not due to cell death by cytotoxicity. We also investigated the effect of quercetin on melanogenesis of this cells. B16/F10 melanoma cells were grown for 48h in the presence of 0.01~50$\mu\textrm{g}$/ml quercetin and the total melanin contents were measured. Quercetin stimulated melanization of the cells in low concentrations (0.01~20$\mu\textrm{g}$/ml), whereas it inhibited melanization in high concentrations (30~50$\mu\textrm{g}$/ml). It was observed that quercetin differently regulates melanogenesis of B16/F10 melanoma cells dependent on its concentrations.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Antiproliferative Effects of Quercetin through Cell Cycle Arrest and Apoptosis in Human Breast Cancer MDA-MB-453 Cells
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
2008 .01
-
Small Cell Melanoma
Annals of Dermatology
2014 .01
-
Antitumor and apoptotic effect of quercetin in human melanoma cells involving JNK/P38 MAPK signaling activation
한국실험동물학회 학술발표대회 논문집
2019 .01
-
Differential Effects of Quercetin and Quercetin Glycosides on Human α7 Nicotinic Acetylcholine Receptor-Mediated Ion Currents
Biomolecules & Therapeutics(구 응용약물학회지)
2016 .01
-
산수유 물추출물이 B16/F10 melanoma세포주의 멜라닌 생성에 미치는 영향
동의생리병리학회지
2002 .08
-
시엽추출물이 활성산소로 손상된 멜라닌세포종의 멜라닌합성 및 세포생존율에 미치는 영향
동의생리병리학회지
2008 .10
-
인체 멜라닌세포주에서 連翹 추출물의 멜라닌생성 억제기전 연구
동의생리병리학회지
2008 .04
-
Preventive and Therapeutic Effects of Quercetin on Experimental Radiation Induced Lung Injury in Mice
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Quercetin이 마우스의 면역반응에 미치는 영향
약학회지
1991 .01
-
Effect of quercetin on apoptosis of PANC-1 cells
Annals of Surgical Treatment and Research
2013 .12
-
멜라닌 생성과 그 조절
대한화장품학회 심포지움
1996 .01
-
Antioxidant enzyme activities and intracellular reactive oxygen intermediate (ROI) levels of flavonol quercetin in the presence of taurine on Bl6F10 murine melanoma cells.
한국응용약물학회 추계학술발표논문집
2003 .01
-
B16F10 세포에서 Quercetin과 Vitamin E, L-Ascorbic acid, 환원형 글루타치온과의 병용 투여에 의한 활성산소종 발생과 항산화 효소의 활성 변화
약학회지
2003 .01
-
Inhibition of T-cell-Dependent Antibody Production by Quercetin in Mice
Biomolecules & Therapeutics(구 응용약물학회지)
2009 .01
-
Autophagy Inhibition Promotes Quercetin Induced Apoptosis in MG-63 Human Osteosarcoma cells
International Journal of Oral Biology
2015 .01
-
어성초로부터 분리된 Quercetin의 Protein Tyrosine Phosphatase 1B 활성
동의생리병리학회지
2008 .01
-
Anticancer effects of quercetin on KB human oral cancer cells
Oral Biology Research
2012 .01
-
시엽추출물이 활성산소로 손상된 멜라닌세포종의 멜라닌합성 및 세포생존율에 미치는 영향
동의생리병리학회지
2008 .01
-
Quercetin attenuates neuronal cells damage in a middle cerebral artery occlusion animal model and HT-22 cells
한국실험동물학회 학술발표대회 논문집
2018 .07
이 논문의 저자 정보
최근 본 자료
댓글(0)
0