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논문 기본 정보

자료유형
학술저널
저자정보
Mi Ri Kim (Jeonnam Institute of Natural Resources Research) Young Uk Kim (Jeonnam Institute of Natural Resources Research) So Jeong Im (Jeonnam Institute of Natural Resources Research) A Ra Jo (Jeonnam Institute of Natural Resources Research) Gyu Ok Lee (Jeonnam Institute of Natural Resources Research) Ja Won Shin (Jeonnam Institute of Natural Resources Research) Hu Won Kang (Jeonnam Institute of Natural Resources Research) Hak Joon Choi (Jeonnam Institute of Natural Resources Research) Seul Gi Lee (Jeonnam Institute of Natural Resources Research) Cho Een Kim (Jeonnam Institute of Natural Resources Research) Hak Sung Lee (Jeonnam Institute of Natural Resources Research) Jaeyong Kim (Jeonnam Institute of Natural Resources Research) Chul Yung Choi (Jeonnam Institute of Natural Resources Research)
저널정보
한국식품저장유통학회 Food Science and Preservation 한국식품저장유통학회지 제27권 제4호
발행연도
2020.7
수록면
505 - 512 (8page)

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초록· 키워드

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In this study, we aimed to investigate the antioxidant and immunopotentiating effects of leaves of cherry elaeagnus (Elaeagnus multiflora, Em). The leaf, stem, and root of Em have been used in Kampo medicine. There are data on the therapeutic effects of Em fruit, but no information on its leaves. We thus investigated the antioxidant and immunopotentiating effects of Em leaf extract. Balb/c mouse spleen cells were treated with concanavalin A and hot aqueous Em leaf extract (50, 100, and 200 μg/mL), and the effects on spleen cell proliferation and the secretion of interleukin (IL)-2, IL-4, and IL-10 were evaluated. A concentration-dependent increase in the secretion of IL-2 and IL-4 cytokines was observed, with concentrations of 1.86 pg/mL of IL-2 and 37.63 pg/mL of IL-4 when cells were treated with 200 ㎍/mL of the extract. Natural killer (NK) cell activity was determined based on a co-culture of spleen cells and Yac-1 cells. NK activity gradually increased in a concentration-dependent manne. Further, 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity was 58.5% and 2,2ʹ-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) radical scavenging activity was 78.2% with an extract concentration of 200 ㎍/mL. The high antioxidant activity of the hot water extract of Em leaves suggests their potential therapeutic value and warrants further studies.

목차

Abstract
Introduction
Materials and methods
Results and discussion
References

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