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배경: 카베페넴 내성 Acinetobacter baumannii (CRAB)가 중요한 병원 감염의 원인균으로 대두되고있다. 이 연구는 CRAB 감시배양의 효과적인 방법을 결정하기 위해 시행하였다. 방법: CRAB가 정착된 중환자실 입원환자에서 비강과 직장 도말을 동시에 실시하였다. 모든 검체는 CR102가 첨가된 CHROMagar Acinetobacter 배지(CHROMagar), 5 μg/mL 이미페넴이 첨가된MacConkey 배지(MCA-IPM), 5 μg/mL 이미페넴이 첨가된 triptic soy broth 배지(TSB-IPM)에 접종하였고, CRAB 검출률을 비교하였다. 결과: 37명의 환자로부터 시행한 비강 혹은 직장 도말 중 한 곳에서라도 CRAB가 검출된 비율은CHROMagar에서 89.2% (33/37), MCA-IPM에서 78.4% (29/37), TSB-IPM에서 86.5% (23/27)였다. 결론: CRAB 감시배양에서 CHROMagar를 이용하여 비강과 직장 도말을 동시에 시행하는 것이효과적인 방법임을 알 수 있었다.
목차
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참고문헌 (13)
참고문헌 신청
Gilad J / 2008 / Treatment options for multidrug-resistant Acinetobacter species / Drugs 68:165~189
Agusti C / 2001 / Short-term effect of the application of selective decontamination of the digestive tract on different body site reservoir ICU patients colonized by multi-resistant Acinetobacter baumannii / J Antimicrob Chemother 49:205~208
Heritier C / 2005 / A nosocomial outbreak of Acinetobacter baumannii isolates expressing the carbapenem-hydrolysing oxacillinase OXA-58 / J Antimicrob Chemother 55:115~118
Marchaim D / 2007 / Surveillance cultures and duration of carriage of multidrug-resistant Acinetobacter baumannii / J Clin Microbiol 45:1551~1555
Maragakis LL / 2008 / Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment option / Clin Infect Dis 15:1254~1263
Agusti C / 2001 / Short-term effect of the application of selective decontamination of the digestive tract on different body site reservoir ICU patients colonized by multi-resistant Acinetobacter baumannii / J Antimicrob Chemother 49:205~208
Heritier C / 2005 / A nosocomial outbreak of Acinetobacter baumannii isolates expressing the carbapenem-hydrolysing oxacillinase OXA-58 / J Antimicrob Chemother 55:115~118
Marchaim D / 2007 / Surveillance cultures and duration of carriage of multidrug-resistant Acinetobacter baumannii / J Clin Microbiol 45:1551~1555
Maragakis LL / 2008 / Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment option / Clin Infect Dis 15:1254~1263
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