지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 131 - 137 (7page)
이용수
초록· 키워드
오류제보하기
Background: Among various diseases that accompany pain, complex regional pain syndrome (CRPS) is one of the most frustrating for patients and physicians. Recently, many studies have shown functional and anatomical abnormalities in the brains of patients with CRPS. The calcium-related signaling pathway is important in various physiologic processes via calmodulin (CaM) and calcium-calmodulin kinase 2 (CaMK2). To investigate the cerebral mechanism of CRPS, we measured changes in CaM and CaMK2 expression in the cerebrum in CRPS animal models.Methods: The chronic post-ischemia pain model was employed for CRPS model gen-eration. After generation of the animal models, the animals were categorized into three groups based on changes in the withdrawal threshold for the affected limb: CRPS-positive (P), CRPS-negative (N), and control (C) groups. Western blot analysis was performed to measure CaM and CaMK2 expression in the rat cerebrum.Results: Animals with a decreased withdrawal threshold (group P) showed a signifi-cant increment in cerebral CaM and CaMK2 expression (P = 0.013 and P = 0.021, respectively). However, groups N and C showed no difference in CaM and CaMK2 expression.Conclusions: The calcium-mediated cerebral process occurs after peripheral injury in CRPS, and there can be a relationship between the cerebrum and the pathogen-esis of CRPS.
목차
등록된 정보가 없습니다.
참고문헌 (43)
참고문헌 신청
Stanton-Hicks M / 1998 / Complex regional pain syndromes : guidelines for therapy / Clin J Pain 14:155~166
Moseley GL / 2005 / Distorted body image in complex regional pain syndrome / Neurology 65:773
Moseley GL / 2008 / Thinking about movement hurts : the effect of motor imagery on pain and swelling in people with chronic arm pain / Arthritis Rheum 59:623~631
Acerra NE / 2005 / Dysynchiria : watching the mirror image of the unaffected limb elicits pain on the affected side / Neurology 65:751~753
Geha PY / 2008 / The brain in chronic CRPS pain : abnormal gray-white matter interactions in emotional and autonomic regions / Neuron 60:570~581
Moseley GL / 2005 / Distorted body image in complex regional pain syndrome / Neurology 65:773
Moseley GL / 2008 / Thinking about movement hurts : the effect of motor imagery on pain and swelling in people with chronic arm pain / Arthritis Rheum 59:623~631
Acerra NE / 2005 / Dysynchiria : watching the mirror image of the unaffected limb elicits pain on the affected side / Neurology 65:751~753
Geha PY / 2008 / The brain in chronic CRPS pain : abnormal gray-white matter interactions in emotional and autonomic regions / Neuron 60:570~581
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
증상 발현 후 6시간 이내 응급실 도착한 급성심근경색증에서 hs-CRP 및 CRP velocity와 재원 기간 내 단기 예후와의 상관 관계
대한응급의학회지
2021 .01
-
한국 성인에서 우울증과 hs-CRP 혈중 농도와의 연관성: 국민건강영양조사 2018년 자료 이용
Korean Journal of Family Practice
2021 .01
-
뇌졸중 이후의 복합부위통증증후군
뇌신경재활
2016 .01
-
급성 신우신염 환자의 중증도 예측에 CRP velocity의 유용성
대한응급의학회지
2015 .01
-
Complex regional pain syndrome in the young male population: a retrospective study of 200 Korean young male patients
The Korean Journal of Pain
2019 .01
-
Predictive Value of Sympathetic Skin Response in Diagnosing Complex Regional Pain Syndrome: A Case-Control Study
Annals of Rehabilitation Medicine
2015 .01
-
하지 피부색의 변화를 동반한 골절 후 발생 복합부위 통증 증후군(CRPS) 치험 1례
한방안이비인후피부과학회지
2024 .05
-
Utilization of C-Reactive Protein Test as a Predictor of Lung Injury in Patients with Coronavirus Disease 2019
Laboratory Medicine Online
2021 .01
-
Relationship Between HbA1c and Complex Regional Pain Syndrome in Stroke Patients With Type 2 Diabetes Mellitus
Annals of Rehabilitation Medicine
2016 .01
-
High-Sensitivity C-Reactive Protein Can Reflect Small Airway Obstruction in Childhood Asthma
Yonsei Medical Journal
2016 .01
-
Higher Serum C Reactive Protein Determined C Reactive Protein Single-Nucleotide Polymorphisms Are Involved in Inherited Depression
PSYCHIATRY INVESTIGATION
2018 .01
-
A Korean nationwide investigation of the national trend of complex regional pain syndrome vis-a-vis age-structural transformations
The Korean Journal of Pain
2021 .01
-
통합적인 한방치료로 호전된 복합부위통증증후군(CRPS) type1 환자 1례 보고
대한한방내과학회지
2018 .01
-
The role of C-reactive protein ratio in predicting mortality in patients with Fournier gangrene
Annals of Coloproctology
2023 .06
-
CRPS를 위한 작업치료 프로그램이 통증과 상지기능에 미치는 영향: 예비연구
고령자･치매작업치료학회지
2023 .05
-
The effect of shift work on high sensitivity C-reactive protein level among female workers
대한직업환경의학회지
2019 .05
-
Disease Phenotype, Activity and Clinical Course Prediction Based on C-Reactive Protein Levels at Diagnosis in Patients with Crohn’s Disease: Results from the CONNECT Study
Gut and Liver
2016 .01
-
C-reactive Protein Concentration Is Associated With a Higher Risk of Mortality in a Rural Korean Population
예방의학회지
2016 .01
-
C-reactive Protein Overexpression in the Background Liver of Hepatitis B Virus–Associated Hepatocellular Carcinoma Is a Prognostic Biomarker
Journal of Pathology and Translational Medicine
2018 .01
-
Decreased C-reactive protein induces abnormal vascular structure in a rat model of liver dysfunction induced by bile duct ligation
Clinical and Molecular Hepatology
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0