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Effect of Sequential Intrastromal Corneal Ring Segment Implantation and Corneal Collagen Crosslinking in Corneal Ectasia
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논문 기본 정보

Type
Academic journal
Author
Journal
대한안과학회 Korean Journal of Ophthalmology Korean Journal of Ophthalmology 제33권 제6호 KCI Accredited Journals
Published
2019.1
Pages
528 - 538 (11page)

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Effect of Sequential Intrastromal Corneal Ring Segment Implantation and Corneal Collagen Crosslinking in Corneal Ectasia
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Abstract· Keywords

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Purpose: To assess the clinical efficacy of sequential intrastromal corneal ring segment (ICRS) implantation andcorneal crosslinking (CXL) in corneal ectasia. Methods: This retrospective case series included eight eyes in which both ICRS implantation and CXL hadbeen performed. CXL was performed within 1 month after ICRS implantation. The clinical outcomes (visualacuity, refractive errors, keratometry, and topographic indices) of these patients were compared with those ofpatients who had undergone only ICRS implantation (eight eyes) or CXL (20 eyes). Results: Greater improvement in uncorrected visual acuity was observed in the ICRS + CXL group than inthe ICRS or CXL alone groups at both 6 (p = 0.008) and 12 months (p = 0.028). Refractive errors of sphereand spherical equivalent were significantly reduced in both the ICRS (p = 0.002 at 6 months, p = 0.004 at12 months) and ICRS + CXL groups (p < 0.001 at both 6 and 12 months). Keratometric values including themaximum, minimum, and average were significantly reduced in all 3 groups at postoperative 6 and 12 months;however, the greatest reductions were observed in the ICRS + CXL group (all p < 0.001). Conclusions: ICRS implantation followed by CXL within 1 month seems to be effective, and may be superior toICRS or CXL alone in improving visual acuity and reducing refractive errors and keratometric values.

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Parker JS / 2015 / Treatment options for advanced keratoconus : a review / Surv Ophthalmol 60:459~480 google schola Rabinowitz YS / 2007 / Intacs for keratoconus / Curr Opin Ophthalmol 18:279~283 google schola Raiskup F / 2015 / Corneal collagen crosslinking with riboflavin and ultraviolet-A light in progressive keratoconus : ten-year results / J Cataract Refract Surg 41:41~46 google schola Spoerl E / 1998 / Induction of cross-links in corneal tissue / Exp Eye Res 66:97~103 google schola Wollensak G / 2003 / Ribof lavin/ultraviolet-a-induced collagen crosslinking for the treatment of keratoconus / Am J Ophthalmol 135:620~627 google schola

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