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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 222 - 224 (3page)
이용수
초록· 키워드
오류제보하기
Some studies have shown that augmenting buspirone with antidepressant has similar efficacy as the combination with two antidepressants in patients with major depressive disorder (MDD). Some researchers assume that the antidepressant boosting effect of buspirone is revealed under a poop-out state, which means a phenomenon where some patients having an initial response to an antidepressant may worsen or not improve any more even though they continue treatment because of serotonin depletion. Loudness dependence of auditory evoked potential (LDAEP) is a reliable marker of central serotonergic activity, and is inversely correlated with central serotonergic activity. Thus LDAEP will be a biological marker for prediction of treatment response with buspirone augmentation with SSRI because it can measure central serotonergic activity such as serotonin depletion. Two cases will be introduced and the literature evidence about whether LDAEP can predict the treatment response of buspirone augmentation in patients with MDD will be reviewed.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Ionescu DF / 2015 / Pharmacological approaches to the challenge of treatment-resistant depression / Dialogues Clin Neurosci 17:111~126
Loane C / 2012 / Buspirone: what is it all about? / Brain Res 1461:111~118
Trivedi MH / 2006 / Medication augmentation after the failure of SSRIs for depression / N Engl J Med 354:1243~1252
Targum SD / 2014 / Identification and treatment of antidepressant tachyphylaxis / Innov Clin Neurosci 11:24~28
Morrissette DA / 2014 / Modulating the serotonin system in the treatment of major depressive disorder / CNS Spectr 19(Suppl 1):57~67
Loane C / 2012 / Buspirone: what is it all about? / Brain Res 1461:111~118
Trivedi MH / 2006 / Medication augmentation after the failure of SSRIs for depression / N Engl J Med 354:1243~1252
Targum SD / 2014 / Identification and treatment of antidepressant tachyphylaxis / Innov Clin Neurosci 11:24~28
Morrissette DA / 2014 / Modulating the serotonin system in the treatment of major depressive disorder / CNS Spectr 19(Suppl 1):57~67
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