지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 255 - 262 (8page)
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초록· 키워드
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Background: Exsanguination is a major cause of death in severe trauma patients. The purpose of this study was to analyze the prognostic impact of the initial lactate level for massive transfusion (MT) in severe trauma. We divided patients according to subgroups of traumatic brain injury (TBI) and non-TBI. Methods: This single-institution retrospective study was conducted on patients who were admitted to hospital for severe trauma between January 2016 and December 2017. TBI was defined by a head Abbreviated Injury Scale ≥3. Receiver operating characteristic analysis was used to analyze the prognostic impact of the lactate level. Multivariate analyses were performed to evaluate the relationship between the MT and lactate level. The primary outcome was MT. Results: Of the 553 patients, MT was performed in 62 patients (11.2%). The area under the curve (AUC) for the lactate level for predicting MT was 0.779 (95% confidence interval [CI], 0.742 to 0.813). The AUCs for lactate level in the TBI and non-TBI patients were 0.690 (95% CI, 0.627 to 0.747) and 0.842 (95% CI, 0.796 to 0.881), respectively. In multivariate analyses, the lactate level was independently associated with the MT (odds ratio [OR], 1.179; 95% CI, 1.070 to 1.299). The lactate level was independently associated with MT in non-TBI patients (OR, 1.469; 95% CI, 1.262 to 1.710), but not in TBI patients. Conclusions: The initial lactate level may be a possible prognostic factor for MT in severe trauma. In TBI patients, however, the initial lactate level was not suitable for predicting MT.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Lefering R / 2012 / Epidemiology of in-hospital trauma deaths / Eur J Trauma Emerg Surg 38:3~9
Brown JB / 2015 / Systolic blood pressure criteria in the National Trauma Triage Protocol for geriatric trauma : 110 is the new 90 / J Trauma Acute Care Surg 78:352~359
Kauvar DS / 2006 / Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations / J Trauma 60(6 Suppl):S3~S11
Johnson JJ / 2013 / Initial inferior vena cava diameter on computed tomographic scan independently predicts mortality in severely injured trauma patients / J Trauma Acute Care Surg 74:741~746
Hagiwara A / 2016 / Can early aggressive administration of fresh frozen plasma improve outcomes in patients with severe blunt trauma? : a report by the Japanese Association for the Surgery of Trauma / Shock 45:495~501
Brown JB / 2015 / Systolic blood pressure criteria in the National Trauma Triage Protocol for geriatric trauma : 110 is the new 90 / J Trauma Acute Care Surg 78:352~359
Kauvar DS / 2006 / Impact of hemorrhage on trauma outcome: an overview of epidemiology, clinical presentations, and therapeutic considerations / J Trauma 60(6 Suppl):S3~S11
Johnson JJ / 2013 / Initial inferior vena cava diameter on computed tomographic scan independently predicts mortality in severely injured trauma patients / J Trauma Acute Care Surg 74:741~746
Hagiwara A / 2016 / Can early aggressive administration of fresh frozen plasma improve outcomes in patients with severe blunt trauma? : a report by the Japanese Association for the Surgery of Trauma / Shock 45:495~501
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