지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.6
- 수록면
- 34 - 40 (7page)
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초록· 키워드
오류제보하기
Purpose: The bowel frequency of patients who had undergone rectal resection might be difficult to distinguish from the diarrhea of Clostridium difficile infection (CDI). The change of bowel movement following rectal surgery has been a challenge for the diagnosis of CDI and scarce studies discussed this diagnostic difficulty.
Methods: From January 2004 to January 2018, a total of 8,327 patients in a single tertiary colorectal cancer center was evaluated for CDI, and their medical records were ret rospectively reviewed. Bowel frequency and treatment outcomes were compared between the rectal resection group (RG) and colectomy group (CG). Diagnostic time was defined as the time interval between first diarrhea (more than three times a day) and pathologic confirmation date of CDI.
Results: CDI incidence was 2.3% (17/752) vs. 0.41% (31/7,575) between RG and CG (P<0.001). RG had frequent bowel movements than CG (RG: 13.56±6.16/day vs. CG: 8.39±6.23/day; P=0.010), but the interval between the time of symptom and the time of CDI diagnosis was longer in the RG than in CG (RG: 1.38±3.34 days vs. CG: 0.39±1.16 days). A total of three mortalities has been occurred (RG: 2 vs. CG: 1), and the reasons were delayed diagnosis and omitted treatment.
Conclusion: Patients experienced significant bowel frequency after rectal surgery than after colectomy, and the delayed diagnosis was associated with mortality. Active surveillance for CDI should be performed for the patients who underwent rectal surgery to prevent morbidity and mortality from delayed diagnosis of CDI, but sophisticated guideline also should be evaluated to reduce over-examinations.
Methods: From January 2004 to January 2018, a total of 8,327 patients in a single tertiary colorectal cancer center was evaluated for CDI, and their medical records were ret rospectively reviewed. Bowel frequency and treatment outcomes were compared between the rectal resection group (RG) and colectomy group (CG). Diagnostic time was defined as the time interval between first diarrhea (more than three times a day) and pathologic confirmation date of CDI.
Results: CDI incidence was 2.3% (17/752) vs. 0.41% (31/7,575) between RG and CG (P<0.001). RG had frequent bowel movements than CG (RG: 13.56±6.16/day vs. CG: 8.39±6.23/day; P=0.010), but the interval between the time of symptom and the time of CDI diagnosis was longer in the RG than in CG (RG: 1.38±3.34 days vs. CG: 0.39±1.16 days). A total of three mortalities has been occurred (RG: 2 vs. CG: 1), and the reasons were delayed diagnosis and omitted treatment.
Conclusion: Patients experienced significant bowel frequency after rectal surgery than after colectomy, and the delayed diagnosis was associated with mortality. Active surveillance for CDI should be performed for the patients who underwent rectal surgery to prevent morbidity and mortality from delayed diagnosis of CDI, but sophisticated guideline also should be evaluated to reduce over-examinations.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (18)
참고문헌 신청
Damle RN / 2014 / Clostridium difficile infection after colorectal surgery: a rare but costly complication / J Gastrointest Surg 18:1804~1811
염창호 / 2010 / Risk Factors for the Development of Clostridium difficileassociated Colitis after Colorectal Cancer Surgery / Annals of Coloproctolgy 26(5):329~333
Vonberg RP / 2008 / Infection control measures to limit the spread of Clostridium difficile / Clin Microbiol Infect 14(Suppl 5):2~20
Zheng Y / 2017 / Clostridium difficile colonization in preoperative colorectal cancer patients / Oncotarget 8:11877~11886
Slimings C / 2014 / Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis / J Antimicrob Chemother 69:881~891
염창호 / 2010 / Risk Factors for the Development of Clostridium difficileassociated Colitis after Colorectal Cancer Surgery / Annals of Coloproctolgy 26(5):329~333
Vonberg RP / 2008 / Infection control measures to limit the spread of Clostridium difficile / Clin Microbiol Infect 14(Suppl 5):2~20
Zheng Y / 2017 / Clostridium difficile colonization in preoperative colorectal cancer patients / Oncotarget 8:11877~11886
Slimings C / 2014 / Antibiotics and hospital-acquired Clostridium difficile infection: update of systematic review and meta-analysis / J Antimicrob Chemother 69:881~891
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