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논문 기본 정보

자료유형
학술저널
저자정보
Min-Seok Cho (Catholic University of Pusan) Seokyoun Choi (Catholic University of Pusan) Gilhyun Lee (Dong Eui University) Mi Ha Ju (Dong-A University College of Medicine) Seok-Cheol Choi (Catholic University of Pusan)
저널정보
대한의생명과학회 대한의생명과학회지 대한의생명과학회지 제25권 제4호
발행연도
2019.12
수록면
339 - 347 (9page)

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Saururus chinensis (SC) belongs to the dicotyledonous plants, and its roots, leaves and flowers are white, so it is named three hundred and seconds. It is mainly distributed in Korea, China and Japan. In Korea, it is a native plant distributed in Jejudo and Jirisan areas. It has been known to improve blood circulation, anticarcinogenic effects and purge. However, studies of the efficacy on digestive system is few. This study was conducted to evaluate the effects of oral administered-SC extract in loperimide-induced constipation rats. The amount, weight and water content of the stools were measured. The number and type of stools in the large intestines were measured, and the amount of intestinal mucus was analyzed by serological analysis and histologic special staining. The severity of constipation in SC groups was significantly less than that in control group (non-SC rats). Digital Image processing also showed weaker inflammation on the large intestines of SC groups than that of control group (non-SC group). Especially, with increased dose dependent manner of SC extract, the amount and integrity of intestinal mucus increased. These results suggest that SC extract may prevent the symptoms of constipation.

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