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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 138 - 147 (10page)
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In this study, we examined antioxidative effects and the anti-adipogenesis effect of different parts of Cudrania tricuspidata (C), and Morus alba (M). Total polyphenol contents were highest in M-root (34.56±0.045 mg GAE/g), and there was no significant difference, between C-root and M-leaf. Total flavonoid contents of C-root were highest (23.07±0.004 mg QE/g). To examine antioxidant activities of C and M extracts, DPPH and ABTS radical scavenging activity, and FRAP assay, was used. Results show that antioxidant activities of C and M extracts increased, in a dose-dependent manner. Adipocytes are generated by preadipocyte differentiation, during adipogenesis. Matured adipocytes accumulate in abnormal and cause obesity. We investigated effects of leaf and root extracts of C and M, on lipid accumulation, in 3T3-L1 adipocytes. Changes in cell morphology, and degrees of lipid accumulation in adipocytes, were evaluated by Oil Red O staining. Root extracts of C and M, reduced lipid content in a dose-dependent manner. Therefore, root extracts of C and M, may be good candidates for managing obesity.
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참고문헌 (49)
참고문헌 신청
Ahn EK / 2012 / 1β-hydroxy-2-oxopomolic acid isolated from Agrimonia pilosa extract inhibits adipogenesis in 3T3-L1 cells / Biol Pharm Bull 35:643~649
Beecher GR / 2003 / Overview of dietary flavonoids : Nomenclature, occurrence and intake / J Nutr 133:3248S~3254S
Benzie IFF / 1996 / The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay / Anal Biochem 239:70~76
Blois MS / 1958 / Antioxidant determinations by the use of a stable free radical / Nature 181:1199~1200
Carmichael J / 1987 / Evaluation of a tetrazolium-based semiautomated colorimetric assay : Assessment of chemosensitivity testing / Cancer Res 47:936~942
Beecher GR / 2003 / Overview of dietary flavonoids : Nomenclature, occurrence and intake / J Nutr 133:3248S~3254S
Benzie IFF / 1996 / The ferric reducing ability of plasma (FRAP) as a measure of "antioxidant power": The FRAP assay / Anal Biochem 239:70~76
Blois MS / 1958 / Antioxidant determinations by the use of a stable free radical / Nature 181:1199~1200
Carmichael J / 1987 / Evaluation of a tetrazolium-based semiautomated colorimetric assay : Assessment of chemosensitivity testing / Cancer Res 47:936~942
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