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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
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- 1 - 8 (8page)
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Treating adult low-grade gliomas (LGGs) is particularly challenging due to the highly infiltrative nature of this type of brain cancer. Although surgery, radiotherapy, and chemotherapy are the mainstay treatment modalities for LGGs, the optimal combination management plan for a particular patient based on individual symptoms and the risk of treatment-induced toxicity remains unclear. This review highlights the competency and limitations of standard treatment options while providing an essential therapeutic update regarding current clinical trials aimed at implementing targeted therapies with morbidity rates lower than those for current LGG treatments and also augmenting the killing of cancerous cells while maintaining an improved quality of life.
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참고문헌 (50)
참고문헌 신청
Louis DN / 2016 / The 2016 World Health Organization classification of tumors of the central nervous system : a summary / Acta Neuropathol 131:803~820
Cancer Genome Atlas Research Network / 2015 / Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas / N Engl J Med 372:2481~2498
Ostrom QT / 2015 / CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012 / Neuro Oncol 17(Suppl 4):iv1~iv62
Shaw E / 2002 / Prospective randomized trial of low-versus high-dose radiation therapy in adults with supratentorial low-grade glioma : initial report of a North Central Cancer Treatment Group/Radiation Therapy Oncology Group/Eastern Cooperative Oncology Group study / J Clin Oncol 20:2267~2276
Bogdańska MU / 2017 / A mathematical model describes the malignant transformation of low grade gliomas : prognostic implications / PLoS One 12:e0179999
Cancer Genome Atlas Research Network / 2015 / Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas / N Engl J Med 372:2481~2498
Ostrom QT / 2015 / CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2008-2012 / Neuro Oncol 17(Suppl 4):iv1~iv62
Shaw E / 2002 / Prospective randomized trial of low-versus high-dose radiation therapy in adults with supratentorial low-grade glioma : initial report of a North Central Cancer Treatment Group/Radiation Therapy Oncology Group/Eastern Cooperative Oncology Group study / J Clin Oncol 20:2267~2276
Bogdańska MU / 2017 / A mathematical model describes the malignant transformation of low grade gliomas : prognostic implications / PLoS One 12:e0179999
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