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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 185 - 188 (4page)
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초록· 키워드
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The three-dimensional (3-D) shape of erythrocytes is strongly associated with various diseases. However, conventional optical imaging approaches with Wright's staining only provide information on two-dimensional morphology. Here, we employed optical diffraction tomography (ODT), a label-free 3-D quantitative phase imaging technique, and observed uniquely shaped red blood cells (RBCs) in the peripheral blood of a patient diagnosed with myelodysplastic syndrome. Peripheral blood samples were collected when the patient visited our hospital for his two out-patient follow-ups in May 2018. The 3-D tomograms of randomly chosen RBCs were reconstructed using a commercial ODT setup. From the reconstructed 3-D RBCs, 37.5% and 32.8% of RBCs demonstrated cup-like shapes at the first and the second out-patient follow-up, respectively. Even though this is a single case report, the finding is novel and can be a potential dyserythropoietic feature found in peripheral blood.
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등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Jaffe ES / 2017 / Hematopathology / Elsevier :793~794
Kim Y / 2014 / Profiling individual human red blood cells using common-path diffraction optical tomography / Sci Rep 4:6659
Kim K / 2013 / Real-time visualization of 3-D dynamic microscopic objects using optical diffraction tomography / Opt Express 21:32269~32278
Salsbury AJ / 1967 / New method for detecting changes in the surface appearance of human red blood cells / J Clin Pathol 20:603~610
Shin S / 2015 / Active illumination using a digital micromirror device for quantitative phase imaging / Opt Lett 40:5407~5410
Kim Y / 2014 / Profiling individual human red blood cells using common-path diffraction optical tomography / Sci Rep 4:6659
Kim K / 2013 / Real-time visualization of 3-D dynamic microscopic objects using optical diffraction tomography / Opt Express 21:32269~32278
Salsbury AJ / 1967 / New method for detecting changes in the surface appearance of human red blood cells / J Clin Pathol 20:603~610
Shin S / 2015 / Active illumination using a digital micromirror device for quantitative phase imaging / Opt Lett 40:5407~5410
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