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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.10
- 수록면
- 192 - 204 (13page)
이용수
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해당 논문이 위치하는 상위 비율을 의미합니다.
초록· 키워드
오류제보하기
Neuropeptide oxytocin serves as a neuromodulator in the brain and as a hormone in the body. Oxytocin as a hypothalamic hormone causes contractions during the second and third stages of labor and lets milk come out during breast feeding. As a neuromodulator, oxytocin that influences social affiliative behavior plays an important role in social cognition and emotional learning. Recent studies showed that oxytocin affects basic fear learning and fear extinction precess in a social context. Furthermore, oxytocin has anxiolytic and stress-dampening effects when combined with social support, i.e. a safety stimuli. Also, oxytocin enhances basic emotional learning precesses of both acquisition and extinction of an emotional content while simultaneously decreasing pain experiences. Oxytocin has involvement in attachment, and is shown to improve positive affective behavior in romantic relations. Social buffering effects that social touch and emotional and physical intimacy play crucial roles in coping with negative effects are assumed to be mediated through brain oxytocin mechanisms. Researches indicate that oxytocin significantly inhibits hypothalamic-pituitary-adrenal axis activity in response to stress, and consequently reduces cortisol levels. Conversely, exposure to stress triggers the release of intrahypothalamic and plasma oxytocin. These results suggest that oxytocin may be a new pavement in treating post-traumatic stress disorder and depression.
목차
서론
옥시토신과 중추신경계
옥시토신과 학습의 관계
공포 학습(Fear Learning)과 안전 학습(Safety Learning)
임상적 의의
결론
참고문헌
참고문헌 (97)
참고문헌 신청
Renaud LP / 1991 / Neurophysiology and neuropharmacology of hypothalamic magnocellular neurons secreting vasopressin and oxytocin / Prog Neurobiol 36:131~169
Gimpl G / 2001 / The oxytocin receptor system:structure, function, and regulation / Physiol Rev 81:629~683
Sawchenko PE / 1982 / Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat / J Comp Neurol 205:260~272
Caffé AR / 1987 / Vasopressin cells in the medial amygdala of the rat project to the lateral septum and ventral hippocampus / J Comp Neurol 26:237~252
De Vries GJ / 1983 / The origin of vasopressinergic and oxytocinergic innervation of the rat brain with special reference to the lateral septum / Brain Res 273:307~317
Gimpl G / 2001 / The oxytocin receptor system:structure, function, and regulation / Physiol Rev 81:629~683
Sawchenko PE / 1982 / Immunohistochemical identification of neurons in the paraventricular nucleus of the hypothalamus that project to the medulla or to the spinal cord in the rat / J Comp Neurol 205:260~272
Caffé AR / 1987 / Vasopressin cells in the medial amygdala of the rat project to the lateral septum and ventral hippocampus / J Comp Neurol 26:237~252
De Vries GJ / 1983 / The origin of vasopressinergic and oxytocinergic innervation of the rat brain with special reference to the lateral septum / Brain Res 273:307~317
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