지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: To investigate the role of sex-hormonal changes in idiopathic carpal tunnel syndrome (CTS) among post-menopausal women through measuring estrogen receptor (ER) expression in their transverse carpal ligament (TCL) and serum estrogen level, as well as determine the correlation between these factors and electrodiagnostic parameters and Boston score.Methods: Biopsy samples of TCL were collected from 12 postmenopausal women who had undergone surgery for severe idiopathic CTS; control specimens were collected from 10 postmenopausal women without CTS who had undergone surgery for the other hand pathologies. To determine the distributions of ER in TCL, histological and immunohistochemical examinations were performed. Serum estrogen level was also measured. Electrodiagnosis and Boston questionnaire were used for CTS severity and determination of the patients’ function.Results: ER expression in TCL and serum estrogen level were not significantly different in the case group compared to the control group (P = 0.79 and P = 0.88, respectively). Also, there was no correlation between ER expression or serum estrogen level and electrodiagnostic parameters or Boston score.Conclusions: Sex hormones cannot still be considered as the etiology of idiopathic CTS in postmenopausal women. The role of other factors such as wrist ratio and narrower outlet in females compared to the males should be considered along with hormonal changes. (J Menopausal Med 2016;22:80-86)
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참고문헌 (22)
참고문헌 신청
Hashempur MH / 2014 / Effect of Linum usitatissimum L. (linseed) oil on mild and moderate carpal tunnel syndrome: a randomized, double-blind, placebo-controlled clinical trial / Daru 22:43
de Krom MC / 1992 / Carpal tunnel syndrome: prevalence in the general population / J Clin Epidemiol 45:373~376
Kim JK / 2010 / The expression of estrogen receptors in the tenosynovium of postmenopausal women with idiopathic carpal tunnel syndrome / J Orthop Res 28:1469~1474
Toesca A / 2008 / Estrogen and progesterone receptors in carpal tunnel syndrome / Cell Biol Int 32:75~79
Sharifi-Mollayousefi A / 2008 / Assessment of body mass index and hand anthropometric measurements as independent risk factors for carpal tunnel syndrome / Folia Morphol 67:36~42
de Krom MC / 1992 / Carpal tunnel syndrome: prevalence in the general population / J Clin Epidemiol 45:373~376
Kim JK / 2010 / The expression of estrogen receptors in the tenosynovium of postmenopausal women with idiopathic carpal tunnel syndrome / J Orthop Res 28:1469~1474
Toesca A / 2008 / Estrogen and progesterone receptors in carpal tunnel syndrome / Cell Biol Int 32:75~79
Sharifi-Mollayousefi A / 2008 / Assessment of body mass index and hand anthropometric measurements as independent risk factors for carpal tunnel syndrome / Folia Morphol 67:36~42
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