지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Objectives: This study aimed to compare the efficacy of tibolone and transdermal estrogen in treating menopausal symptoms in postmenopausal women with an intact uterus. Methods: Overall, 26 women consumed tibolone orally and 31 women received transdermal estrogen gel mixed with progestogen. The menopause rating scale (MRS) was used to assess their menopausal symptoms at their first outpatient visit and 6 months later. Results: The transdermal estrogen group showed significant improvements in more items of the MRS questionnaire. There was a favorable change in body weight in the transdermal estrogen group compared with that in the tibolone group. Depressive mood, irritability, physical and mental exhaustion, sexual and bladder problems, and joint and muscular discomfort improved only in the transdermal estrogen group, whereas heart discomfort and vaginal dryness improved only in the tibolone group. Nevertheless, the intergroup differences in each item were insignificant after adjusting for body mass index and hypertension, which differed before treatment. Conclusions: Both the therapeutic options improved menopausal symptoms within 6 months of use. However, transdermal estrogen appeared to be more effective in preventing weight gain in menopausal women than tibolone.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Shifren JL / 2012 / Berek & Novak's gynecology / Lippincott Williams & Wilkins :1233~1248
Schiff I / 1979 / Effects of estrogens on sleep and psychological state of hypogonadal women / JAMA 242:2405~2407
Anderson GL / 2004 / Effects of conjugated equine estrogen in postmenopausal women with hysterectomy : the Women's Health Initiative randomized controlled trial / JAMA 291:1701~1712
Hulley SB / 2004 / The WHI estrogen-alone trial--do things look any better? / JAMA 291:1769~1771
Goodman MP / 2012 / Are all estrogens created equal? A review of oral vs. transdermal therapy / J Womens Health (Larchmt) 21:161~169
Schiff I / 1979 / Effects of estrogens on sleep and psychological state of hypogonadal women / JAMA 242:2405~2407
Anderson GL / 2004 / Effects of conjugated equine estrogen in postmenopausal women with hysterectomy : the Women's Health Initiative randomized controlled trial / JAMA 291:1701~1712
Hulley SB / 2004 / The WHI estrogen-alone trial--do things look any better? / JAMA 291:1769~1771
Goodman MP / 2012 / Are all estrogens created equal? A review of oral vs. transdermal therapy / J Womens Health (Larchmt) 21:161~169
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