지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 578 - 584 (7page)
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초록· 키워드
오류제보하기
Background/Aims: Peptic ulcer disease (PUD) is a common condition, but is difficult to detect in asymptomatic individuals. We aimed to investigate the prevalence of symptomatic and asymptomatic PUD during screening endoscopy and to identify risk factors for the presence of symptoms in patients with PUD.
Methods: We investigated subjects who underwent a health inspection, including endoscopy of the upper gastrointestinal (GI) tract and a serum anti-Helicobacter pylori IgG assay, and who completed a self-report questionnaire about their symptoms.
Results: Of the 12,852 subjects included in the study, 124 (1.0%) had symptomatic PUD and 309 (2.4%) had asymptomatic PUD. Old age, current smoking, and H. pylori infection were independent risk factors for symptomatic and asymptomatic PUD. Use of non-steroidal anti-inflammatory drugs (NSAIDs) was an independent risk factor only for symptomatic PUD (p=0.040). Compared to subjects with asymptomatic PUD, subjects with symptomatic PUD were more likely to have active-stage ulcers (p=0.002) and to drink more heavily (p=0.005).
Conclusions: Use of NSAIDs is a risk factor for symptomatic PUD, but not for asymptomatic PUD. Excessive alcohol consumption and active-stage ulcers in patients with PUD are related to the presence of gastroduodenal symptoms.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Al Dhahab H / 2013 / State-of-the-art management of acute bleeding peptic ulcer disease / Saudi J Gastroenterol 19 : 195 ~ 204
Atherton JC / 1995 / Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration / J
Bode G / 2002 / Dyspeptic symptoms in middle-aged to old adults: the role of Helicobacter pylori infection, and various demographic and lifestyle factors / J Intern Med 252
Choi HS / 2014 / Combining the serum pepsinogen level and Helicobacter pylori antibody test for predicting the histology of gastric neoplasm / J Dig Dis 15 : 293 ~ 298
D’Elios MM / 2009 / Inflammation, immunity, and vaccines for Helicobacter pylori / Helicobacter 14 (Suppl 1) : 21 ~ 28
Atherton JC / 1995 / Mosaicism in vacuolating cytotoxin alleles of Helicobacter pylori. Association of specific vacA types with cytotoxin production and peptic ulceration / J
Bode G / 2002 / Dyspeptic symptoms in middle-aged to old adults: the role of Helicobacter pylori infection, and various demographic and lifestyle factors / J Intern Med 252
Choi HS / 2014 / Combining the serum pepsinogen level and Helicobacter pylori antibody test for predicting the histology of gastric neoplasm / J Dig Dis 15 : 293 ~ 298
D’Elios MM / 2009 / Inflammation, immunity, and vaccines for Helicobacter pylori / Helicobacter 14 (Suppl 1) : 21 ~ 28
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