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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 147 - 153 (7page)
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초록· 키워드
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ObjectiveTo assess the efficacy and safety of ultrasound-guided intragestational injection of methotrexate (MTX) and systemic intramuscular MTX in the management of cesarean scar pregnancies. MethodsThis was a retrospective case-control study that included women diagnosed with cesarean scar pregnancy at CHA Bundang Medical Center unit between 2009 and 2015. The 26 cases were managed with local injection of MTX under ultrasound guidance and 15 cases were treated with systemic intramuscular of MTX. After the procedure, serial follow-up sonographic examination and serum beta-human chorionic gonadotropin (β-hCG) measurement were performed. ResultsThe mean initial β-hCG level was 20,610.73 mIU/mL and ranged from 263.00–71,316.50 mIU/mL. Mean gestational age was 6.3 weeks and ranged from 4.8 to 8.5 weeks. The majority of ectopic cases were treated successfully and follow-up β-hCG level declined abruptly following the first dose of MTX. The rate of success of local MTX treatment was significantly higher than that of systemic MTX treatment. It was 93.75% vs. 73.33%, respectively (P<0.05). ConclusionUltrasound-guided intragestational injection of MTX is an effective method for the management of cesarean scar pregnancies and is associated with minimal side effects and high treatment success.
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Clark EA / 2011 / Long-term maternal morbidity associated with repeat cesarean delivery / Am J Obstet Gynecol 205:S2~S10
Seow KM / 2000 / Methotrexate for cesarean scar pregnancy after in vitro fertilization and embryo transfer. A case report / J Reprod Med 45:754~757
Alammari R / 2017 / Vaginal hysterectomy for treatment of cervical ectopic pregnancy / Obstet Gynecol 129:63~65
Ash A / 2007 / Caesarean scar pregnancy / BJOG 114:253~263
Timor-Tritsch IE / 2014 / Cesarean scar pregnancy and early placenta accreta share common histology / Ultrasound Obstet Gynecol 43:383~395
Seow KM / 2000 / Methotrexate for cesarean scar pregnancy after in vitro fertilization and embryo transfer. A case report / J Reprod Med 45:754~757
Alammari R / 2017 / Vaginal hysterectomy for treatment of cervical ectopic pregnancy / Obstet Gynecol 129:63~65
Ash A / 2007 / Caesarean scar pregnancy / BJOG 114:253~263
Timor-Tritsch IE / 2014 / Cesarean scar pregnancy and early placenta accreta share common histology / Ultrasound Obstet Gynecol 43:383~395
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