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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 88 - 94 (7page)
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ObjectiveTo detect the possible clinicopathologic factors associated with parametrial involvement in patients with stage IB1 cervical cancer and to identify a cohort of patients who may benefit from less radical surgery. MethodsWe retrospectively reviewed 120 patients who underwent radical hysterectomy and pelvic lymphadenectomy as treatment for stage IB1 cervical cancer. ResultsOverall, 18 (15.0%) patients had parametrial tumor involvement. Tumor size larger than 2 cm, invasion depth greater than 1 cm, presence of lymphovascular space involvement (LVSI), corpus involvement, and positive lymph nodes were statistically associated with parametrial involvement. Multivariate analysis for other factors showed invasion depth >1 cm (P=0.029), and corpus involvement (P=0.022) were significantly associated with parametrial involvement. A subgroup with tumor size smaller than 2 cm showed no parametrial involvement, regardless of invasion depth or presence of LVSI. ConclusionTumor size smaller than 2 cm showed no parametrial involvement, regardless of invasion depth or presence of LVSI. Invasion depth >1 cm and corpus involvement were significantly associated with parametrial involvement in multivariate analysis. These finding may suggest that tumor size may a strong predictor of parametrial involvement in International Federation of Gynecology and Obstetrics stage IB1 cervical cancer, which can be used to select a subgroup population for less radical surgery.
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참고문헌 (21)
참고문헌 신청
Covens A / 2002 / How important is removal of the parametrium at surgery for carcinoma of the cervix? / Gynecol Oncol 84:145~149
Benedetti-Panici P / 2000 / Early cervical carcinoma: the natural history of lymph node involvement redefined on the basis of thorough parametrectomy and giant section study / Cancer 88:2267~2274
Delgado G / 1989 / A prospective surgical pathological study of stage I squamous carcinoma of the cervix: a Gynecologic Oncology Group Study / Gynecol Oncol 35:314~320
노주원 / 2015 / Efficacy and oncologic safety of nerve-sparing radical hysterectomy for cervical cancer: a randomized controlled trial / Journal of Gynecologic Oncology 26(2):90~99
Kim MK / 2010 / Feasibility of less radical surgery for superficially invasive carcinoma of the cervix / Gynecol Oncol 119:187~191
Benedetti-Panici P / 2000 / Early cervical carcinoma: the natural history of lymph node involvement redefined on the basis of thorough parametrectomy and giant section study / Cancer 88:2267~2274
Delgado G / 1989 / A prospective surgical pathological study of stage I squamous carcinoma of the cervix: a Gynecologic Oncology Group Study / Gynecol Oncol 35:314~320
노주원 / 2015 / Efficacy and oncologic safety of nerve-sparing radical hysterectomy for cervical cancer: a randomized controlled trial / Journal of Gynecologic Oncology 26(2):90~99
Kim MK / 2010 / Feasibility of less radical surgery for superficially invasive carcinoma of the cervix / Gynecol Oncol 119:187~191
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