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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 278 - 287 (10page)
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Background/Aims: Mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach is an uncommon disease. Bone marrow involvement is reported even in patients with only a mucosal lesion. We evaluated the prevalence and risk factors of marrow involvement and its implications for diagnosis and treatment. Methods: In total, 132 patients who were diagnosed with gastric MALT lymphoma at the National Cancer Center in Korea between January 2001 and December 2016 were enrolled in the study. The patient data were collected and analyzed retrospectively. Results: Of the 132 patients, 47 (35.6%) were male, with a median age of 52 years (range, 17 to 81 years). The median follow-up duration was 48.8 months (range, 0.5 to 169.9 months). Helicobacter pylori infection was detected in 82 patients (62.1%). Most patients (80.3%) had stage IE1 according to the modified Ann Arbor staging system. Ninety-two patients underwent bone marrow evaluation, and four patients (4.3%) had marrow involvement. Of these patients, one presented with abdominal lymph node involvement, while the other three had stage IE1 disease if marrow involvement was disregarded. All three patients had no significant symptoms and were monitored after local treatment without evidence of disease aggravation. Conclusions: Bone marrow involvement was found in 4.3% of the patients with gastric MALT lymphoma. Bone marrow examination may be deferred because marrow involvement does not change the treatment options or outcome in gastric MALT lymphoma confined to the stomach wall.
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참고문헌 (32)
참고문헌 신청
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1997 / A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma: the non-Hodgkin's lymphoma classification project / Blood 89:3909~3918
Wotherspoon AC / 1991 / Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma / Lancet 338:1175~1176
Hyjek E / 1988 / Primary B-cell lymphoma of salivary glands and its relationship to myoepithelial sialadenitis / Hum Pathol 19:766~776
Swerdlow SH / 2016 / The 2016 revision of the World Health Organization classification of lymphoid neoplasms / Blood 127:2375~2390
1997 / A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin's lymphoma: the non-Hodgkin's lymphoma classification project / Blood 89:3909~3918
Wotherspoon AC / 1991 / Helicobacter pylori-associated gastritis and primary B-cell gastric lymphoma / Lancet 338:1175~1176
Hyjek E / 1988 / Primary B-cell lymphoma of salivary glands and its relationship to myoepithelial sialadenitis / Hum Pathol 19:766~776
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