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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 163 - 169 (7page)
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초록· 키워드
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Objective: To evaluate the efficacy and safety of prostaglandin (PG) E2 for preterm labor induction and to investigate the predictive factors for the success of vaginal delivery.
Methods: A retrospective cohort study was performed in women (n=155) at 24+0 to 36+6 weeks of gestation who underwent induction of labor using a PGE2 vaginal pessary (10 mg, Propess) from January 2009 to December 2015. Success rates of vaginal delivery according to gestational age at induction and incidence of intrapartum complications such as tachysystole and nonreassuring fetal heart rate were investigated. Multivariable logistic regression analysis was performed to evaluate the predictive factors for success of labor induction.
Results: The vaginal delivery rate was 57% (n=89) and the rate of cesarean delivery after induction was 43% (n=66). According to gestational age, labor induction was successful in 16.7%, 50.0%, and 62.8% of patients at 24 to 31, 32 to 33, and 34 to 36 weeks, showing a stepwise increase (P=0.006). There were 18 cases (11%) of fetal distress, 9 cases (5.8%) of tachysystole, and 6 cases (3.8%) of massive postpartum bleeding (>1,000 mL). After adjusting for confounding factors, multiparity (odds ratio [OR], 8.47; 95% confidence interval [CI], 3.10 to 23.14), younger maternal age (OR, 0.84; 95% CI, 0.75 to 0.94), advanced gestational age at induction (OR, 1.06; 95% CI, 1.02 to 1.09), rupture of membranes (OR, 11.83; 95% CI, 3.55 to 39.40), and the Bishop score change after removal of PGE2 (OR, 2.19; 95% CI, 1.0 to 4.8) were significant predictors of successful preterm vaginal delivery.
Conclusion: An understanding of the principal predictive factors of successful preterm labor induction, as well as the safety of PGE2, will provide useful information when clinicians consult with preterm pregnant women requiring premature delivery.
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등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
ACOG Committee on Practice Bulletins Obstetrics / 2009 / ACOG Practice Bulletin No. 107: Induction of labor / Obstet Gynecol 114 : 386 ~ 397
Abelin Tornblom S / 2002 / Pre-term cervical ripening and labor induction / Eur J Obstet Gynecol Reprod Biol 104 : 120 ~ 123
Anderson AB / 1969 / Relationship between length of gestation and cervical dilatation, uterine contractility, and other factors during pregnancy / Am J Obstet Gynecol 105 :
Ben-Haroush A / 2004 / Mode of delivery in pregnancies with premature rupture of membranes at or before term following induction of labor with vaginal prostaglandin E2 / Am
Blackwell SC / 2001 / Labor induction for the preterm severe pre-eclamptic patient: is it worth the effort? / J Matern Fetal Med 10 : 305 ~ 311
Abelin Tornblom S / 2002 / Pre-term cervical ripening and labor induction / Eur J Obstet Gynecol Reprod Biol 104 : 120 ~ 123
Anderson AB / 1969 / Relationship between length of gestation and cervical dilatation, uterine contractility, and other factors during pregnancy / Am J Obstet Gynecol 105 :
Ben-Haroush A / 2004 / Mode of delivery in pregnancies with premature rupture of membranes at or before term following induction of labor with vaginal prostaglandin E2 / Am
Blackwell SC / 2001 / Labor induction for the preterm severe pre-eclamptic patient: is it worth the effort? / J Matern Fetal Med 10 : 305 ~ 311
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