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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제28권 제7호
- 발행연도
- 2018.1
- 수록면
- 1,061 - 1,067 (7page)
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The anti-melanogenic effects of the extract of Angelica tenuissima (AT) root and the extract of AT root fermented by Aspergillus oryzae (FAT) were investigated. These effects were determined by measuring the inhibitory activity of AT and FAT on melanin production in B16F10 melanocytes and with in vitro tyrosinase activity assays. The AT extract inhibited melanin production at concentrations above 250 μg/ml, and this inhibitory effect was significantly enhanced by the fermentation process with A. oryzae. HPLC analysis resulted in the isolation of two active compounds from both the AT and FAT extracts. Their chemical structures were identified as decursin and Z-ligustilide through comparison with previously reported NMR data. The decursin and Z-ligustilide contents were increased in the FAT extract and could be responsible for its enhanced inhibitory effects on melanin production and tyrosinase activity compared with that of the AT extract
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참고문헌 (19)
참고문헌 신청
Pham AK / 2014 / Cosmeceuticals for children: should you care? / Curr. Opin. Pediatr. 26:446~451
Desmedt B / 2016 / Overview of skin whitening agents with an insight into the illegal cosmetic market in Europe / J. Eur. Acad. Dermatol. Venereol. 30:943~950
Han BH / 1998 / International Collation of Traditional and Folk Medicine / World Scientific Publishing Co. Pte. Ltd.
Prasanna Weeratunga / 2016 / Interferon-mediated antiviral activities of Angelica tenuissima Nakai and its active components / The Journal of Microbiology 54(1):57~70
Ahn SJ / 2015 / The inhibitory effect of Angelica tenuissima water extract on receptor activator of nuclear factor-kappa-B ligand-induced osteoclast differentiation and bone resorbing activity of mature osteoclasts / Am. J. Chin. Med. 43:715~729
Desmedt B / 2016 / Overview of skin whitening agents with an insight into the illegal cosmetic market in Europe / J. Eur. Acad. Dermatol. Venereol. 30:943~950
Han BH / 1998 / International Collation of Traditional and Folk Medicine / World Scientific Publishing Co. Pte. Ltd.
Prasanna Weeratunga / 2016 / Interferon-mediated antiviral activities of Angelica tenuissima Nakai and its active components / The Journal of Microbiology 54(1):57~70
Ahn SJ / 2015 / The inhibitory effect of Angelica tenuissima water extract on receptor activator of nuclear factor-kappa-B ligand-induced osteoclast differentiation and bone resorbing activity of mature osteoclasts / Am. J. Chin. Med. 43:715~729
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