지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제25권 제10호
- 발행연도
- 2015.1
- 수록면
- 1,653 - 1,659 (7page)
이용수
초록· 키워드
오류제보하기
Epothilone, which is produced by the myxobacterium Sorangium cellulosum, contributes significant value in medicinal development. However, under submerged culture conditions, S. cellulosum will accumulate to form bacterial clumps, which hinder nutrient and metabolite transportation. Therefore, the production of epothilone by liquid fermentation is limited. In this study, diatomite-based porous ceramics were made from diatomite, paraffin, and poremaking agent (saw dust). Appropriate methods to modify the porous ceramics were also identified. After optimizing the preparation and modification conditions, we determined the optimal prescription to prepare high-performance porous ceramics. The structure of porous ceramics can provide a solid surface area where S. cellulosum can grow and metabolize to prevent the formation of bacterial clumps. S. cellulosum cells that do not form clumps will change their erratic metabolic behavior under submerged culture conditions. As a result, the unstable production of epothilone by this strain can be changed in the fermentation process, and the purpose of increasing epothilone production can be achieved. After 8 days of fermentation under optimized conditions, the epothilone yield reached 90.2 mg/l, which was increased four times compared with the fermentation without porous ceramics.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Abbott SL / 2003 / Biochemical properties of a newly described Escherichia species, Escherichia albertii / J. Clin. Microbiol 41 : 4852 ~ 4854
Almeida C / 2004 / Use of two different carriers in a packed bed reactor for endopolygalacturonase production by a yeast strain / Process Biochem 40 : 1937 ~ 1942
Berengut D. / 2006 / Statisties for experiments: design, innovation, and discovery / Am. Stat 60 : 341 ~ 342
Davies J / 2012 / Introducing the parvome: bioactive compounds in the microbial world / ACS Chem. Biol 7 : 252 ~ 259
Devi S / 1999 / Optimization of critical parameters for immobilization of Streptomyces clavuligerus on alginate gel matrix for cephamycin C production / World J. Microbiol. B
Almeida C / 2004 / Use of two different carriers in a packed bed reactor for endopolygalacturonase production by a yeast strain / Process Biochem 40 : 1937 ~ 1942
Berengut D. / 2006 / Statisties for experiments: design, innovation, and discovery / Am. Stat 60 : 341 ~ 342
Davies J / 2012 / Introducing the parvome: bioactive compounds in the microbial world / ACS Chem. Biol 7 : 252 ~ 259
Devi S / 1999 / Optimization of critical parameters for immobilization of Streptomyces clavuligerus on alginate gel matrix for cephamycin C production / World J. Microbiol. B
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Botrytis cinerea와 Colletotrichum acutatum에 항균활성을 갖는 점액세균 Sorangium cellulosum에 대한 아종 분류 및 길항 특성 연구
Research in Plant Disease(식물병연구)
2018 .09
-
목분 기포제를 이용한 산업부산물 소재 다공성 세라믹에 의한 산성광산배수의 처리특성 연구
한국환경과학회지
2018 .02
-
RT-PCR과 다공성 세라믹 큐브를 이용한 벼줄무늬잎마름바이러스 간편 진단
Research in Plant Disease(식물병연구)
2015 .12
-
Pt and Pt-Ir porous ceramic electrodes for highly sensitive room temperature ammonia sensor
한국진공학회 학술발표회초록집
2016 .08
-
Fungal Fermentation of Lignocellulosic Biomass for Itaconic and Fumaric Acid Production
Journal of Microbiology and Biotechnology
2017 .01
-
Surface characterization of porous nanomaterials in environmental applications
한국분석과학회 학술대회
2017 .11
-
Ba0.77Ca0.23TiO3: Ho/Yb ceramics for temperature sensing applications
한국진공학회 학술발표회초록집
2015 .02
-
Hysteresis Characteristics of Graphene/Porous Si Heterostructure
새물리
2022 .12
-
Identification of Electricity Generation Based on Water Infiltration in Porous Structure
한국진공학회 학술발표회초록집
2020 .08
-
Preparation of metal-complexed porous carbon membrane and application to adsorption of gas
한국분석과학회 학술대회
2016 .11
-
Comparison of Liquid and Solid-State Fermentation Processes for the Production of Enzymes and Beta-Glucan from Hulled Barley
Journal of Microbiology and Biotechnology
2022 .03
-
Preparation of Nb-doped (Nd0.55Li0.36)TiO₃ ceramics and its thermoelectric properties
한국진공학회 학술발표회초록집
2016 .08
-
Synthesis of porous Mn3O4 microtubes for electrochemical applications
한국진공학회 학술발표회초록집
2018 .02
-
Microbiota and Physicochemical Analysis on Traditional Kocho Fermentation Enhancer to Reduce Losses (Gammaa) in the Highlands of Ethiopia
한국미생물·생명공학회지
2018 .01
-
Effects of Temperature on Bacterial Communities, Metabolites, and Flavoring Compounds during Kimchi Fermentation
한국미생물학회 학술대회논문집
2019 .04
-
Optimization of a Fermentation Process to Improve Microbial Production of Heme
한국미생물학회 학술대회논문집
2022 .10
-
양자화학 계산을 이용한 물 분자의 Clumped 안정동위원소의 분배계수 특성
한국암석학회 학술발표회 논문집
2023 .06
-
Experimental Study of Local Thermal Equilibrium in Porous Medium Through Tracer Tests
대한지질학회 학술대회
2018 .10
-
Dynamics of Bacterial and Viral Communities during Kimchi Fermentation
한국미생물학회 학술대회논문집
2021 .08
-
Fabrication of Metal Oxide-Coated Porous Polyimide and its Applications
한국분석과학회 학술대회
2022 .11
이 논문의 저자 정보
최근 본 자료
댓글(0)
0