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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제25권 제5호
- 발행연도
- 2015.1
- 수록면
- 658 - 661 (4page)
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초록· 키워드
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Genes encoding enzymes with sequence similarity to hopanoids biosynthetic enzymes of other organisms were cloned from the hopanoid (hop) gene cluster of Streptomyces peucetius ATCC 27952 and transformed into Streptomyces venezuelae YJ028. The cloned fragments contained four genes, all transcribed in one direction. These genes encode polypeptides that resemble polyprenyl diphosphate synthase (hopD), squalene-phytoene synthases (hopAB), and squalenehopene cyclase (hopE). These enzymes are sufficient for the formation of the pentacyclic triterpenoid lipid, hopene. The formation of hopene was verified by gas chromatography/ mass spectrometry.
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참고문헌 (24)
참고문헌 신청
[학술지(정기간행물)
Anding C / 1976 / Nonspecific biosynthesis of hopane triterpenes in a cell-free system from Acetobacter rancens / J. Am. Chem. Soc 98 : 1274 ~ 1275
Bisseret P / 1983 / A direct study of the cohesion of lecithin bilayers: the effect of hopanoids and α,ω- dihydroxycarotenoids / Biochem. Biophys. Res. Commun 110 : 320 ~ 3
Bligh EG / 1959 / A rapid method of total lipid extraction and purification / Can. J. Biochem. Physiol 37 : 911 ~ 917
Corey EJ / 1966 / 2,3-Oxidosqualene, an intermediate in the biological synthesis of sterols from squalene / J. Am. Chem. Soc 88 : 4750 ~ 4751
Anding C / 1976 / Nonspecific biosynthesis of hopane triterpenes in a cell-free system from Acetobacter rancens / J. Am. Chem. Soc 98 : 1274 ~ 1275
Bisseret P / 1983 / A direct study of the cohesion of lecithin bilayers: the effect of hopanoids and α,ω- dihydroxycarotenoids / Biochem. Biophys. Res. Commun 110 : 320 ~ 3
Bligh EG / 1959 / A rapid method of total lipid extraction and purification / Can. J. Biochem. Physiol 37 : 911 ~ 917
Corey EJ / 1966 / 2,3-Oxidosqualene, an intermediate in the biological synthesis of sterols from squalene / J. Am. Chem. Soc 88 : 4750 ~ 4751
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