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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제19권 제10호
- 발행연도
- 2009.1
- 수록면
- 1,139 - 1,141 (3page)
이용수
초록· 키워드
오류제보하기
Clitocybin D, a novel human neutrophil elastase inhibitor,
was isolated from the culture broth of Clitocybe aurantiaca.
This compound was purified by solvent extraction, silica
gel column chromatography, Sephadex LH-20 column
chromatography, and preparative HPLC. The compound
was determined to be 4-(4,6-dihydroxy-3-methoxy-3Hisoindol-
1-yl)-benzoic acid on the basis of 1D and 2D
NMRs and MS spectroscopic analysis. Analysis of the
human neutrophil elastase (HNE) inhibitory activity of
the isolated compound revealed that it showed significant
HNE inhibitory activity with an IC50 value of 17.8 μM.
목차
등록된 정보가 없습니다.
참고문헌 (12)
참고문헌 신청
Antonicelli, F. / 2007 / Elastin-elastases and inflamm-aging / Curr. Top. Dev. Biol 79 : 99 ~ 155
Arnone, A. / 1993 / Secondary mold metabolites. Part 42. Eleganthol, a sesquiterpene from Clitocybe elegans / Phytochemistry 32 : 1493 ~ 1497
Bernstein, E. F. / 1996 / The effect of photodamage on dermal extracellular matrix / Clin. Dermatol 14 : 143 ~ 151
Bradshaw, A. P. / 1982 / 4a- Hydroxydihydroilludin M. A new sesquiterpenoid metabolite of Clitocybe illudens / Phytochemistry 21 : 942 ~ 943
Guang-Hua Xu / 2009 / Free Radical Scavenging and Antielastase Activities of Flavonoids from the Fruits of Thuja orientalis / Archives of Pharmacal Research 32 (2) : 275 ~ 2
Arnone, A. / 1993 / Secondary mold metabolites. Part 42. Eleganthol, a sesquiterpene from Clitocybe elegans / Phytochemistry 32 : 1493 ~ 1497
Bernstein, E. F. / 1996 / The effect of photodamage on dermal extracellular matrix / Clin. Dermatol 14 : 143 ~ 151
Bradshaw, A. P. / 1982 / 4a- Hydroxydihydroilludin M. A new sesquiterpenoid metabolite of Clitocybe illudens / Phytochemistry 21 : 942 ~ 943
Guang-Hua Xu / 2009 / Free Radical Scavenging and Antielastase Activities of Flavonoids from the Fruits of Thuja orientalis / Archives of Pharmacal Research 32 (2) : 275 ~ 2
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논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
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