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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제18권 제5호
- 발행연도
- 2008.1
- 수록면
- 837 - 844 (8page)
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Glucose (xylose) isomerases from Streptomyces sp. have been used for the production of high fructose corn syrup for industrial purposes. An 11-kb DNA fragment containing the xyl gene cluster was isolated from Streptomyces lividans TK24 and its nucleotide sequences were analyzed. It was found that the xyl gene cluster contained a putative transcriptional repressor (xylR), xylulokinase (xylB), and xylose isomerase (xylA) genes. The transcriptional directions of the xylB and xylA genes were divergent, which is consistent to those found in other streptomycetes. A gene encoding XylR was located downstream of the xylB gene in the same direction, and its mutant strain produced xylose isomerase regardless of xylose in the media. The enzyme expression level in the mutant was 4.6 times higher than that in the parent strain under xylose-induced condition.
Even in the absence of xylose, the mutant strain produce over 60% of enzyme compared with the xylose-induced condition. Gel mobility shift assay showed that XylR was able to bind to the putative xyl promoter, and its binding was inhibited by the addition of xylose in vitro. This result suggested that XylR acts as a repressor in the S. lividans xylose operon
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참고문헌 (22)
참고문헌 신청
[학술
Bejar, S. H. / 1994 / Construction of a new strain of Streptomyces violaceoniger, having strong, constitutive and stable glucose-isomerase activity. Biotechnol / Lett 16 : 12
Bhosale, S. H. / 1996 / Molecular and industrial aspects of glucose isomerase. Microbiol / Rev 60 : 280 ~ 300
Bhosale, S. H. / 1996 / Molecular cloning and expression of the glucose/xylose isomerase gene from Streptomyces sp. NCIM 2730 in Escherichia coli. FEMS Microbiol / Lett 145 :
Bierman, M. / 1992 / Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp / Gene 116 : 43 ~ 49
Bejar, S. H. / 1994 / Construction of a new strain of Streptomyces violaceoniger, having strong, constitutive and stable glucose-isomerase activity. Biotechnol / Lett 16 : 12
Bhosale, S. H. / 1996 / Molecular and industrial aspects of glucose isomerase. Microbiol / Rev 60 : 280 ~ 300
Bhosale, S. H. / 1996 / Molecular cloning and expression of the glucose/xylose isomerase gene from Streptomyces sp. NCIM 2730 in Escherichia coli. FEMS Microbiol / Lett 145 :
Bierman, M. / 1992 / Plasmid cloning vectors for the conjugal transfer of DNA from Escherichia coli to Streptomyces spp / Gene 116 : 43 ~ 49
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Purification and Properties of D-Xylose Isomerase from Lactococcus sp. JK-8
생명과학회지
2004 .08
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Specific Expression Patterns of xyl1, xyl2, and xyl3 in Response to Different Sugars in Pichia stipitis
Journal of Microbiology and Biotechnology
2010 .01
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Molecular Cloning and Expression of a Thermostable Xylose (Glucose) Isomerase Gene, xylA, from Streptomyces chibaensis J-59
The Journal of Microbiology
2005 .02
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Characterization of D-Xylose Isomerase from Streptomyces albus
미생물학회지
1978 .06
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Expression of D-Xylose Isomerase Gene in Saccaromyces cerevisiae
생명과학
1993 .01
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활엽수로부터 D-xylose의 분리 및 에탄올 생산
목재공학(Journal of the Korean Wood Science and Technology)
1991 .01
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Electrostatic Immobilization of D-Xylose Isomerase to a Cation Exchanger for the Conversion of D-Xylose to D-Xylulose
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2012 .01
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한국식품조리과학회지
1996 .01
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Overexpressions of xylA and xylB in Klebsiella pneumoniae Lead to Enhanced 1,3-Propanediol Production by Cofermentation of Glycerol and Xylose
Journal of Microbiology and Biotechnology
2016 .01
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D-xylose 발효효모의 분리 및 성질
미생물학회지
1990 .12
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Streptomyces canus와 Streptomyces malachiticus의 Xylose Isomerase에 관하여
미생물학회지
1977 .03
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D-Xylose as a sugar complement regulates blood glucose levels by suppressing phosphoenolpyruvate carboxylase (PEPCK) in streptozotocin-nicotinamide-induced diabetic rats and by enhancing glucose uptake in vitro
Nutrition Research and Practice
2016 .02
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D-Xylose as a sugar complement regulates blood glucose levels by suppressing phosphoenolpyruvate carboxylase (PEPCK) in streptozotocin-nicotinamide-induced diabetic rats and by enhancing glucose uptake in vitro
Nutrition Research and Practice
2016 .02
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Effects of Oxygen Supply and Mixed Sugar Concentration on D-Ribose Production by a Transketolase-Deficient Bacillus subtilis SPK1
Journal of Microbiology and Biotechnology
2013 .01
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Caramelization 온도별 반응속도와 반응 생성물의 유지에 대한 항산화효과에 관한 연구
한국식품조리과학회지
1995 .01
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Coconut-derived D-xylose affects postprandial glucose and insulin responses in healthy individuals
Nutrition Research and Practice
2011 .12
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Coconut-derived D-xylose affects postprandial glucose and insulin responses in healthy individuals
Nutrition Research and Practice
2011 .12
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A New Strategy to Improve the Efficiency and Sustainability of Candida parapsilosis Catalyzing Deracemization of (R,S)-1-Phenyl-1,2-Ethanediol Under Non-Growing Conditions: Increase of NADPH Availability
Journal of Microbiology and Biotechnology
2009 .01
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Crystal Structure and Biochemical Characterization of Xylose Isomerase from Piromyces sp. E2
Journal of Microbiology and Biotechnology
2018 .01
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Cloning and Characterization of a Heterologous Gene Stimulating Antibiotic Production in Streptomyces lividans TK-24
The Journal of Microbiology
1999 .06
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