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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제16권 제10호
- 발행연도
- 2006.1
- 수록면
- 1,656 - 1,659 (4page)
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초록· 키워드
오류제보하기
Natural surfactins are a mixture of isoforms thatdifer slightly in their physiological properties. In previousresearch, we obtained surfactin A, B, C, and D from theBacilus subtilis complex BC1212. We found that surfactin Cinhibited nitric oxide (NO)-production and suppressed theexpression of pro-inflammatory cytokine mRNA, which wasstimulated by 1g/ml of lipopolysacharide (LPS) in murineRAW264.7 cels. In order to compare the anti-inflamatoryLPS-induced NO production and the pro-inflammatory cytokineexpression level. Surfactin C inhibited the inhibition of LPS-induced NO production in murine macrophage RAW264.7 cellsthe most. In addition, surfactin C was superior to other surfactin’ssubtypes regarding inhibiting the expression of induciblenitric oxide synthase (iNOS) and monocyte chemoattractantprotein 1 (MCP-1). Finally, the anti-inflammatory activity ofsurfactin C is the most potent, compared with surfactin A, B,and D.
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참고문헌 (16)
참고문헌 신청
Arima, K / 1968 / Surfactin, a crystalline peptidelipid surfactant produced by Bacillus subtilis: Isolation, characterization and its inhibition of fibrin clot formation / Bi
Bernheimer, A. W / 1970 / Nature and properties of a cytolytic agent produced by Bacillus subtilis / J. Gen. Microbiol. 61 : 361 ~ 369
Boisvert, W. A / 2004 / Modulation of atherogenesis by chemokines / Trends Cardiovasc. Med. 14 : 161 ~ 165
Charo, I. F / 2004 / Chemokines in the pathogenesis of vascular disease / Circ. Res. 95 : 858 ~ 866
Cho, J. Y / 2006 / Radical scavenging and anti-inflammatory activity of extracts from Opuntia humifusa Raf. / J. Pharm. Pharmacol. 58 : 113 ~ 119
Bernheimer, A. W / 1970 / Nature and properties of a cytolytic agent produced by Bacillus subtilis / J. Gen. Microbiol. 61 : 361 ~ 369
Boisvert, W. A / 2004 / Modulation of atherogenesis by chemokines / Trends Cardiovasc. Med. 14 : 161 ~ 165
Charo, I. F / 2004 / Chemokines in the pathogenesis of vascular disease / Circ. Res. 95 : 858 ~ 866
Cho, J. Y / 2006 / Radical scavenging and anti-inflammatory activity of extracts from Opuntia humifusa Raf. / J. Pharm. Pharmacol. 58 : 113 ~ 119
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