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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제19권 제5호
- 발행연도
- 2009.1
- 수록면
- 455 - 461 (7page)
이용수
초록· 키워드
오류제보하기
There is a significant amount of experimental evidence
suggesting that polysaccharides from mushrooms enhance
the host immune system by activating various mechanisms
in immune cells, including macrophages. In this study,
polysaccharides from Lentinus edodes were found to
stimulate the functional activation of macrophages to
secrete inflammatory mediators and cytokines and increase
the phagocytotic uptake. The chemical properties of the
stimulatory polysaccharides, CPFN-G-I, CPBN-G, and
CPBA-G, were determined based on their monosaccharide
composition, which mainly consisted of glucose and mannose.
According to FT-IR and GC/MS, the structure of CPFNG-
I, purified from the fruiting body of L. edodes, was
found to consist of a β-1,6-branched-β-1,4-glucan, whereas
CPBN-G and CPBA-G, purified from the liquid culture
broth, were found to be composed of a heteromannan.
The configuration of the β-linkage and triple helical
conformation of each polysaccharide were confirmed using
a Fungi-Fluor kit and Congo red, respectively.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Benzamini, E. / 1991 / Immunology: A Short Course / Wiley-Liss Inc : 51 ~ 58
Blumenkrantz, N. / 1973 / New method for quantitative determination of uronic acids / Anal. Biochem 54 : 484 ~ 489
Bradford, M. M. / 1976 / A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding / Anal. Biochem 72 :
Carmichael, J. / 1987 / Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing / Cancer Res 47 : 936 ~ 942
Chaplin, M. F. / 1986 / Carbohydrate Analysis. A Practical Approach / Oxford IRL Press
Blumenkrantz, N. / 1973 / New method for quantitative determination of uronic acids / Anal. Biochem 54 : 484 ~ 489
Bradford, M. M. / 1976 / A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein dye binding / Anal. Biochem 72 :
Carmichael, J. / 1987 / Evaluation of a tetrazolium-based semiautomated colorimetric assay: Assessment of chemosensitivity testing / Cancer Res 47 : 936 ~ 942
Chaplin, M. F. / 1986 / Carbohydrate Analysis. A Practical Approach / Oxford IRL Press
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