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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제18권 제8호
- 발행연도
- 2008.1
- 수록면
- 1,416 - 1,422 (7page)
이용수
초록· 키워드
오류제보하기
Epothilone and its analogs are a potent new class of anticancer
compounds produced by myxobacteria. Thus, in an effort
to identify new myxobacterial strains producing epothilone
and its analogs, cellulose-degrading myxobacteria were
isolated from Korean soils, and 13 strains carrying epothilone
biosynthetic gene homologs were screened using a
polymerase chain reaction. A migration assay revealed that
Sorangium cellulosum KYC3013, 3016, 3017, and 3018 all
produced microtubule-stabilizing compounds, and an LCMS/
MS analysis showed that S. cellulosum KYC3013
synthesized epothilone A.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Bollag, D. M. / 1995 / Epothilones, a new class of microtubule-stabilizing agents with a taxol-like mechanism of action / Cancer Res 55 : 2325 ~ 2333
Dawid, W. / 2000 / Biology and global distribution of myxobacteria in soils. FEMS Microbiol / Rev 24 : 403 ~ 427
Frykman, S. A. / 2005 / Assessment of fed-batch, semicontinuous, and continuous epothilone D production processes. Biotechnol / Prog 21 : 1102 ~ 1108
Fumoleau, P. / 2007 / Novel tubulin-targeting agents: Anticancer activity and pharmacologic profile of epothilones and related analogues. Ann / Oncol 5 : v9 ~ v15
Gerth, K. / 1996 / Epothilones A and B: Antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physicochemical and biological properties / A
Dawid, W. / 2000 / Biology and global distribution of myxobacteria in soils. FEMS Microbiol / Rev 24 : 403 ~ 427
Frykman, S. A. / 2005 / Assessment of fed-batch, semicontinuous, and continuous epothilone D production processes. Biotechnol / Prog 21 : 1102 ~ 1108
Fumoleau, P. / 2007 / Novel tubulin-targeting agents: Anticancer activity and pharmacologic profile of epothilones and related analogues. Ann / Oncol 5 : v9 ~ v15
Gerth, K. / 1996 / Epothilones A and B: Antifungal and cytotoxic compounds from Sorangium cellulosum (Myxobacteria). Production, physicochemical and biological properties / A
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Selective Production of Epothilone B by Heterologous Expression of Propionyl-CoA Synthetase in Sorangium cellulosum
Journal of Microbiology and Biotechnology
2008 .01
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Enhanced Production of Epothilones by Carbon Sources in Sorangiumcellulosum
Journal of Microbiology and Biotechnology
2006 .01
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Enhanced Production of Epothilone by Immobilized Sorangium cellulosum in Porous Ceramics
Journal of Microbiology and Biotechnology
2015 .01
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Sorangium cellulosum 균주들의 에포틸론 생합성 유전자 보존
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Correlation Between Sorangium cellulosum Subgroups and Their Potential for Secondary Metabolite Production
Journal of Microbiology and Biotechnology
2013 .01
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Soraphen 생합성 유전자군을 갖는 점액세균의 분리
한국미생물·생명공학회지
2009 .01
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Cellulase 유전자 염기서열에 기초한 Sorangium cellulosum 균주들의 계통분류
한국미생물·생명공학회지
2011 .01
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셀룰로오스 분해성 점액세균 Sorangium cellulosum의 분리
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2009 .03
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Repeated Batch Production of Epothilone B by Immobilized Sorangiumcellulosum
Journal of Microbiology and Biotechnology
2007 .01
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Selection and a 3-Year Field Trial of Sorangium cellulosum KYC 3262 Against Anthracnose in Hot Pepper
The Plant Pathology Journal
2014 .09
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Soraphinol C, a New Free-Radical Scavenger from Sorangium cellulosum
Journal of Microbiology and Biotechnology
2008 .01
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점액세균 Sorangium cellulosum이 생산하는 약제내성 암세포의 증식억제물질
한국미생물·생명공학회지
2004 .01
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Selection of KYC 3270, a Cellulolytic Myxobacteria of Sorangium cellulosum, against Several Phytopathogens and a Potential Biocontrol Agent against Gray Mold in Stored Fruit
The Plant Pathology Journal
2011 .09
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Detection of Novel Polyketide Synthase Genes in Sorangium cellulosum Isolated in Korea
한국미생물·생명공학회지
2010 .01
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Biocontrol with Myxococcus sp. KYC 1126 Against Anthracnose in Hot Pepper
The Plant Pathology Journal
2011 .06
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Investigation of the Central Carbon Metabolism of Sorangium cellulosum: Metabolic Network Reconstruction and Quantification of Pathway Fluxes
Journal of Microbiology and Biotechnology
2009 .01
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Effects of Myxococcus fulvus KYC4048 Metabolites on Breast Cancer Cell Death
Journal of Microbiology and Biotechnology
2018 .01
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Isolation and Charaterization of Myxobacteria with Proteolytic Activity
한국미생물·생명공학회지
2009 .01
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점액세균 Myxococcus stipitatus KYC4013에 의한 생리활성물질생산
한국미생물·생명공학회지
2014 .01
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