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자료유형
학술저널
저자정보
저널정보
한국피부과학연구원 아시안뷰티화장품학술지 아시안뷰티화장품학술지 제13권 제2호
발행연도
2015.1
수록면
261 - 266 (6page)

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Excessive production of melanin occurs in response to UV-induced DNA damage, skin hyperpigmentation, post-inflammation and so on. There are many reports on anti-oxidant, anti-inflammation, and antimelanogenesis (whitening) activities of plant polyphenols and the relations with each activity, but little reports about blueberry (Vacciniium virgatum ) juice. We investigated here the three activities from Korean blueberry juice. Three in vitro anti-oxidant activities of 1,1-diphenyl-2-picryl hydrazyl (DPPH), 2,2’-azinobis (3-ethylbenzothiazoline-6-sulphonic acid (ABTS), and hydroxyl radical scavenging were evaluated. The antioxidant activities (IC50 of DPPH) of the quercetin, gallic acid, ascorbic acid, and the blueberry juice were 0.03, 0.01, 0.04, and 83.20 mg/mL, respectively. In addition, the results of ABTS test were 0.11, 0.14, 0.06, and 68.00 mg/mL, respectively. At last, hydroxyl radical scavenging activities were 0.28, 0.15, 0.11 and 91.14 mg/mL. Blueberry juice inhibited mushroom tyrosinase activity with an IC50 value of 528 μg/mL, ascorbic acid 14.4 μg/mL, and arbutin 94.3 μg/mL. Moreover, melanin biosynthesis has been decreased in a-MSH treated B16F10 melanoma cells with dose dependent manner. These results suggest that Korean blueberry juice might have potential in the development of depigmenting agents.

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