메뉴 건너뛰기
Library Notice
Institutional Access
If you certify, you can access the articles for free.
Check out your institutions.
ex)Hankuk University, Nuri Motors
Log in Register Help KOR
Subject
Humanities
General Humanities History Philosophy Religious Studies Linguistics and Literature Other Humanities
Social science
General Social Science Business Management Tourism Education Military Science Library and Information Science Law Sociology Journalism and Media Studies Psychological Science Political Science and Diplomacy Geography Public Administration Economics International Trade Anthropology Other Social Science
Natural science
General Natural Science Physics Biology Life Sciences Mathematics/Statistics Astronomy Earth Science Chemistry Other Natural Science
Engineering
General Engineering Architectural Engineering Mechanical Engineering Industrial Engineering Material/Energy Engineering Electrical and Electronic Engineering Marine and Ocean Engineering Chemical Engineering Computer Science Other Engineering
Medical science
General Medical Science Nursing Science Veterinary Pharmacy Traditional Korean Medicine Basic Medicine Clinical Medicine Other Medicine
Agriculture and Fishery
General Agriculture and Fishery Agriculture Fishery Science Food Science Forestry Animal Husbandry Marine Transportation Studies Other Agriculture and Fishery
Art and Kinesiology
General Arts Design Fine Arts Cosmetology Photography Music Fashion Kinesiology Performing Media Arts Other Arts and Kinesiology
Interdisciplinary Studies
Interdisciplinary Research Science and Technology Studies Brain and Cognitive Science Technology Policy Other Interdisciplinary Studies

KOR

Change in Cognitive Function after Antipsychotics Treatment : A Pilot Study of Long-Acting Injectable versus Oral Form
Recommendations
Search

항정신병약물 치료 후 인지기능 변화 차이 연구 : 장기 지속형 주사제와경구제 비교의 예비 연구

논문 기본 정보

Type
Academic journal
Author
Journal
대한조현병학회 대한조현병학회지 대한조현병학회지 제21권 제2호 KCI Accredited Journals
Published
2018.1
Pages
74 - 80 (7page)

Usage

cover
Change in Cognitive Function after Antipsychotics Treatment : A Pilot Study of Long-Acting Injectable versus Oral Form
Ask AI
Recommendations
Search

Abstract· Keywords

Report Errors
Objectives : This study investigated whether long-acting injectable (LAI) paliperidone is different from its oral form in terms of the effect on cognitive function in schizophrenia spectrum and other psychotic disorders. Methods : We reviewed the medical records of patients in Seoul National University Bundang Hospital who were diagnosed as having schizophrenia and/or other psychotic disorders based on DSM-5 from 2016 to 2017. Seven patients were treated with oral paliperidone and 11 were treated with paliperidone palmitate. All patients underwent clinical and neuropsychological assessment, including the Korean version of the MATRICS Consensus Cognitive Battery (MCCB) at their first visit or within one month of their initial treatment. MCCB was repeated within three to 12 months after the initial assessment. Results : There was no significant difference between the two groups in most cognitive domains including speed of processing, attention and vigilance, working memory, verbal learning, visual learning and reasoning and problem solving domain. However, patients treated with paliperidone palmitate showed better improvement in social cognition domain than those taking oral paliperidone. The standardized values of social cognition domain scores had significantly improved over time in patients under paliperidone palmitate, demonstrating a significant time-by-group interaction. Conclusion : Our results show that long-acting injectable paliperidone could be helpful in some aspects of improving cognitive function in schizophrenia spectrum and other psychotic disorders. Further studies with other antipsychotics are necessary to generalize the results.
#Schizophrenia · Long-acting injectables · Cognitive function · Paliperidone

Contents

No content found

References (29)

Add References
Weinberger D / 2003 / Schizophrenia / Blackwell publishing :326~348 google schola Jobe TH / 2005 / Long-term outcome of patients with schizophrenia: a review / Can J Psychiatry 50:892~900 google schola Lieberman JA / 1996 / Factors influencing treatment response and outcome of first-episode schizophrenia: implications for understanding the pathophysiology of schizophrenia / J Clin Psychiatry 57:5~9 google schola Miyamoto S / 2012 / Pharmacological treatment of schizophrenia: a critical review of the pharmacology and clinical effects of current and future therapeutic agents / Mol Psychiatry 17:1206 google schola Bogerts B / 1993 / Hippocampus-amygdala volumes and psychopathology in chronic schizophrenia / Biol Psychiatry 33:236~246 google schola

Recommendations

It is an article recommended by DBpia according to the article similarity. Check out the related articles!

Related Authors

Recently viewed articles

세월호 참사의 현재적 의미와 사회운동의 과제
박래군2016.04
 Involutive Idempotent Uninorm Logics and Pretabularity
Yang EunsukKorean Association for Logic2019
 Covid 19 news data analysis
Hur Tai-seong, Hwang In YongThe Korean Society Of Computer And Information2021.07
 The Modernization Turnaround of Chinese War Film Narration - Focus on 〈The eight hundred〉 -
Yuanyuan Chen, Wonho ChoiThe Korea Contents Society2021.08

Comments(0)

0

Write first comments.