지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제14권 제1호
- 발행연도
- 2016.1
- 수록면
- 96 - 100 (5page)
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초록· 키워드
오류제보하기
Urinary incontinence, although rarely reported, is one of the most important adverse effects of antipsychotic medication. It can be an embarrassing, distressing, and potentially treatment-limiting. Several antipsychotics, including both typical and atypical varieties, are known to induce urinary incontinence. Many antipsychotic drugs target the neural pathways controlling continence by binding to receptors of some neurotransmitters such as serotonin, dopamine, acetylcholine, and adrenaline. Pharmacological management of incontinence should be considered if there is a risk of cessation of the antipsychotic therapy or any decline in patients' compliance. Amitriptyline, desmopressin, ephedrine, and anticholinergics such as oxybutynin and trihexyphenidyl are the most frequently used agents to treat incontinence. We think that the frequency of incontinence is higher than reported in the literature, and that follow-up routines should include a form of standardized screening for all possible adverse effects, including incontinence, of any given antipsychotic. In this article, we report a case of urinary incontinence as an adverse effect of paliperidone palmitate use during maintenance therapy in a patient with schizophrenia.
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참고문헌 (41)
참고문헌 신청
Pandina GJ / 2010 / A randomized, placebo-controlled study to assess the efficacy and safety of 3 doses of paliperidone palmitate in adults with acutely exacerbated schizophrenia / J Clin Psychopharmacol 30:235~244
Dolder C / 2008 / Paliperidone for schizophrenia / Am J Health Syst Pharm 65:403~413
Bishara D / 2010 / Once-monthly paliperidone injection for the treatment of schizophrenia / Neuropsychiatr Dis Treat 6:561~572
Leysen JE / 1994 / Risperidone:a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity / J Clin Psychiatry 55(Suppl):5~12
Schotte A / 1996 / Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding / Psychopharmacology (Berl) 124:57~73
Dolder C / 2008 / Paliperidone for schizophrenia / Am J Health Syst Pharm 65:403~413
Bishara D / 2010 / Once-monthly paliperidone injection for the treatment of schizophrenia / Neuropsychiatr Dis Treat 6:561~572
Leysen JE / 1994 / Risperidone:a novel antipsychotic with balanced serotonin-dopamine antagonism, receptor occupancy profile, and pharmacologic activity / J Clin Psychiatry 55(Suppl):5~12
Schotte A / 1996 / Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding / Psychopharmacology (Berl) 124:57~73
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