지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 173 - 178 (6page)
이용수
초록· 키워드
오류제보하기
Objectives: Medicinal plants are vital sources of bioactive compounds that are useful for the treatment of patients with snake bites or are indirectly applicable for boosting the effects of conventional serum therapy. These plants are being used traditionally by local healers and tribes for the treatment of patients with snake bites and therefore can be used as an alternative against snake envenomation. Scientifically, using the secondary metabolites of plants to neutralize venom enzymes has an extra benefit of being based on traditional knowledge; also, the use of such metabolites for the treatment of patients with snake bites is cheaper and the treatment can be started sooner.
Methods: All the available information on various secondary metabolites exhibiting venom neutralizing ability were collected via electronic search (using Google books, Pubmed, SciFinder, Scirus, Google Scholar, and Web of Science) and articles of peer-reviewed journals.
Results: Recent interest in different plant has focused on isolating and identifying of different phytoconstituents that exhibit Phospholipase A2 activity and other venom enzyme neutralizing ability. In this support convincing evidence in experimental animal models are available. Conclusion: Secondary metabolites are naturally present, have no side effect, are stable for a long time, can be easily stored, and can neutralize a wide range of snake enzymes, such as phospholipase A2, hyaluronidase, protease, L-amino acid oxidase, 5’nucleotidase, etc. The current review presents a compilation of important plant secondary metabolites that are effective against snake venom due to enzyme neutralization.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Aung HT / 2010 / Rosmarinic acid in Argusia argentea inhibits snake venom-induced hemorrhage / J Nat Med 64 (4) : 482 ~ 486
Dhananjaya BL / 2011 / Anti-venom potential of aqueous extract of stem bark of Mangifera indica L. against Daboia russelii (Russell’s viper)venom / Indian J Biochem Biophys
Gomes A / 2010 / Herbs and herbal constituents active against snake bite / Indian J Exp Biol 48 (9) : 865 ~ 878
Gopi K / 2014 / Inhibition of Naja naja venom enzymes by the methanolic extract of Leucas aspera and its chemical profile by GC-MS / Toxicology Reports 1 : 667 ~ 673
Gopi K / 2016 / Quercetin-3-O-rhamnoside from Euphorbia hirta protects against snake venom induced toxicity / Biochim Biophys Acta 1860 (7) : 1528 ~ 1540
Dhananjaya BL / 2011 / Anti-venom potential of aqueous extract of stem bark of Mangifera indica L. against Daboia russelii (Russell’s viper)venom / Indian J Biochem Biophys
Gomes A / 2010 / Herbs and herbal constituents active against snake bite / Indian J Exp Biol 48 (9) : 865 ~ 878
Gopi K / 2014 / Inhibition of Naja naja venom enzymes by the methanolic extract of Leucas aspera and its chemical profile by GC-MS / Toxicology Reports 1 : 667 ~ 673
Gopi K / 2016 / Quercetin-3-O-rhamnoside from Euphorbia hirta protects against snake venom induced toxicity / Biochim Biophys Acta 1860 (7) : 1528 ~ 1540
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