지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 145 - 154 (10page)
이용수
초록· 키워드
오류제보하기
Objectives: The aim of this paper is to investigate the activities of Malaysian local herbs (Clinacanthus nutans Lindau, Strobilanthes crispus, Murdannia bracteata, Elephantopus scaber Linn., Pereskia bleo, Pereskia grandifolia Haw., Vernonia amygdalina, and Swietenia macrophylla King) for anti-hypertensive and vasorelaxant activity. An infrared (IR) macro-fingerprinting technique consisting of conventional fourier transform IR (FTIR), second-derivative IR (SD-IR), and two-dimensional correlation IR (2D-correlation IR) analyses were used to determine the main constituents and the fingerprints of the Malaysian local herbs.
Methods: The herbs were collected, ground into powder form, and then macerated by using three different solvents: distilled water, 50% ethanol, and 95% ethanol, respectively. The potentials of the extracts produced from these herbs for use as vasorelaxants were determined.
Additionally, the fingerprints of these herbs were analyzed by using FTIR spectra, SD-IR spectra, and 2D-correlation IR spectra in order to identify their main constituents and to provide useful information for future pharmacodynamics studies.
Results: Swietenia macrophylla King has the highest potential in terms of vasorelaxant activity, followed by Vernonia amygdalina, Pereskia bleo, Strobilanthes crispus, Elephantopus scaber Linn., Pereskia grandifolia Haw.,Clinacanthus nutans Lindau, and Murdannia bracteata.
The tri-step IR macro-fingerprint of the herbs revealed that most of them contained proteins. Pereskia bleo and Pereskia grandifolia Haw. were found to contain calcium oxalate while Swietenia macrophylla King was found to contain large amounts of flavonoids.
Conclusion: The flavonoid content of the herbs affects their vasorelaxant activity, and the tri-step IR macro- fingerprint method can be used as an analytical tool to determine the activity of a herbal medicine in terms of its vasorelaxant effect.
목차
등록된 정보가 없습니다.
참고문헌 (14)
참고문헌 신청
Upton R / 2010 / American herbal pharmacopoeia: botanical pharmacognosy- microscopic characterization of botanical medicines / CRC Press :800
Tan ML / 2005 / Muhammad TS. Methanolic extract of Pereskia bleo (Kunth) DC.(Cactaceae) induces apoptosis in breast carcinoma, T47-D cell line / J Ethnopharmacol 96(1-2):287~294
Quasie O / 2016 / Four new steroid saponins with highly oxidized side chains from the leaves of Vernonia amygdalina / Phytochem Lett 15:16~20
Chen JJ / 2010 / A new phragmalin-type limonoid and anti-inflammatory constituents from the fruits of Swietenia macrophylla / Food Chem 120(2):379~384
Goh KL / 2000 / Malaysian herbs / Percetakan Advanco Sendirian Berhad :260
Tan ML / 2005 / Muhammad TS. Methanolic extract of Pereskia bleo (Kunth) DC.(Cactaceae) induces apoptosis in breast carcinoma, T47-D cell line / J Ethnopharmacol 96(1-2):287~294
Quasie O / 2016 / Four new steroid saponins with highly oxidized side chains from the leaves of Vernonia amygdalina / Phytochem Lett 15:16~20
Chen JJ / 2010 / A new phragmalin-type limonoid and anti-inflammatory constituents from the fruits of Swietenia macrophylla / Food Chem 120(2):379~384
Goh KL / 2000 / Malaysian herbs / Percetakan Advanco Sendirian Berhad :260
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
氣味와 효능 용어를 활용한 解表藥의 효능 고찰
대한한의학원전학회지
2017 .01
-
Analysis of prescription frequency of herbs in traditional Korean medicine hospital using electronic medical records
대한한의학회지
2019 .12
-
Creation of Novel Antihypertensive Agent via Structure-Activity Relationship Study on Phytochemicals towards Vasorelaxant Activity
Journal of Pharmacopuncture
2020 .01
-
Association of Plasma Ghrelin Levels with Insulin Resistance in Type 2 Diabetes Mellitus among Saudi Subjects
Endocrinology and Metabolism
2017 .01
-
Systematic network analysis of herb formula in Traditional East Asian Medicine discloses synergistic operation of medicinal herb pairs with statistical significance
셀메드
2015 .05
-
텍스트마이닝 기법을 이용한 『상한론』 내의 증상-본초 조합의 탐색적 분석
동의생리병리학회지
2020 .08
-
五味와 효능 용어를 활용한 淸熱藥의 효능 고찰
대한한의학원전학회지
2016 .01
-
HPLC chemical fingerprinting을 이용한 평위산 구성 성분의 추출률 변화 연구
한약정보연구회지
2015 .09
-
Chemical Composition and Antimicrobial Efficiency of Swietenia macrophylla Seed Extract on Clinical Wound Pathogens
Natural Product Sciences
2019 .03
-
The Risk for Insulin Resistance according to the Degree of Non-Alcoholic Fatty Liver Disease in Korean Men
Journal of Korean Medical Science
2016 .01
-
Cardioprotection via mitochondrial transplantation supports fatty acid metabolism in ischemia-reperfusion injured rat heart
The Korean Journal of Physiology & Pharmacology
2024 .05
-
Recent Changes in the Incidence of Thyroid Cancer in Korea between 2005 and 2018: Analysis of Korean National Data
Endocrinology and Metabolism
2022 .10
-
The importance of assessing heavy metals in medicinal herbs: a quantitative study
셀메드
2016 .02
-
Impact of Insulin Resistance on Acetylcholine-Induced Coronary Artery Spasm in Non-Diabetic Patients
Yonsei Medical Journal
2018 .01
-
소청룡탕(小靑龍湯)의 군신좌사(君臣佐使) 배오(配伍) 분석
대한한의학방제학회지
2018 .01
-
Acanthosis nigricans as a clinical marker of insulin resistance among overweight adolescents
Annals of Pediatirc Endocrinology & Metabolism
2019 .01
-
μ-FT-IR을 이용한 정수 내 미세플라스틱의 검출
환경독성보건학회 심포지엄 및 학술대회
2019 .10
-
Vasorelaxant effects of commonly used traditional herbal prescriptions on isolated rat aortic rings
한국실험동물학회 학술발표대회 논문집
2020 .02
-
한방차의 원료로 사용된 한약재 조사연구
대한예방한의학회지
2016 .12
이 논문의 저자 정보
최근 본 자료
댓글(0)
0