지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 317 - 324 (8page)
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초록· 키워드
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Purpose: To assess the association between frailty and osteoporotic vertebral compression fracture (OVCF) and to evaluate the relationship between numbers of OVCFs and frailty. Materials and Methods: We enrolled 760 subjects, including 59 patients (with OVCF) and 701 controls (without OVCF). Successfulmatching provided 56 patient-control pairs. We analyzed principal clinical and demographic information, which included sex, age, height, weight, body mass index (BMI), variable frailty phenotypes, and Oswestry Disability Index (ODI) and EuroQol 5-dimensionquestionnaire (EQ-5D) scores. The association between frailty and OVCF was ascertained. In addition, the degrees of disability and quality of life attributable to frailty were determined. Results: The prevalence of frailty was significantly higher in the OVCF group than in the control group (p<0.001). Most of the frailtyphenotypes, such as exhaustion, physical inactivity, slowness, and handgrip strength, were also significantly observed in the OVCF group. Within the OVCF group, the participants with frailty had significantly higher disability and lower quality of life than those in a robust state (p<0.001 for ODI and EQ-5D). In addition, the multivariate logistic regression analysis demonstrated that the patients with low BMI [odds ratio (OR)=0.704; 95% confidence interval (CI), 0.543−0.913] and ≥3 fractures (OR=9.213; 95% CI, 1.529−55.501) within the OVCF group were associated with higher odds of frailty. Conclusion: The present study showed significant relationships between frailty and OVCF, severity of symptoms, and disability induced by OVCF. Furthermore, frailty could be a causal and/or resulting factor of OVCFs.
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Keevil VL / 2015 / Ageing well: a review of sarcopenia and frailty / Proc Nutr Soc 74:337~347
Clegg A / 2013 / Frailty in elderly people / Lancet 381:752~762
Cooper Z / 2016 / Comparison of frailty measures as predictors of outcomes after orthopedic surgery / J Am Geriatr Soc 64:2464~2471
Li G / 2016 / Frailty change and major osteoporotic fracture in the elderly: data from the global longitudinal study of osteoporosis in women 3-year hamilton cohort / J Bone Miner Res 31:718~724
Walters S / 2016 / The prevalence of frailty in patients admitted to hospital with vertebral fragility fractures / Curr Rheumatol Rev 12:244~247
Clegg A / 2013 / Frailty in elderly people / Lancet 381:752~762
Cooper Z / 2016 / Comparison of frailty measures as predictors of outcomes after orthopedic surgery / J Am Geriatr Soc 64:2464~2471
Li G / 2016 / Frailty change and major osteoporotic fracture in the elderly: data from the global longitudinal study of osteoporosis in women 3-year hamilton cohort / J Bone Miner Res 31:718~724
Walters S / 2016 / The prevalence of frailty in patients admitted to hospital with vertebral fragility fractures / Curr Rheumatol Rev 12:244~247
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