자극음의 조건 변화에 따른 Mismatch Negativity

김리석; Kim; 김보영; 김창근; 이승환; 정성욱; 김재룡

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자료유형: 학술저널

저자정보: 김리석 Kim 김보영 김창근 이승환 정성욱 김재룡

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제49권 제12호

발행연도: 2006.1

수록면: 1,151 - 1,158 (8page)

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Background and Objectives：Infrequent sounds (deviant stimuli) occurring in a sequence of repetitive sounds (standard stimuli)elicit an event-related potential response called the mismatch negativity (MMN) even in the absence of attention to thesesounds. The purposes of these studies are to record the MMNs elicited by the changes of auditory stimuli in stimulation rate,duration and probability in healthy adults and to record the MMNs in healthy children. Subjects and Method：Three studies wereperformed. The subjects were 15 adults in study 1, 20 adults in study 2, and 22 children in study 3. The standard stimulus was 50msec, 750 Hz, 80 dB SPL tone burst. In study 1, the deviant stimulus was 750 Hz, 80 dB SPL tone burst, in which duration of thedeviant stimulus was varied (25, 75, 100, 125, 150 msec) and stimulation rate was varied (0.9/sec, 2/sec). In study 2, the deviantstimulus was 125 msec, 750 Hz, 80 dB SPL tone burst and the probabilities of the deviant stimulus were varied (40, 35, 30, 25,20, 15, 10, 5%). In study 3, the deviant stimulus was 125 msec, 750 Hz, 80 dB SPL tone burst and the probability of the deviantstimulus was 20%. Results：We obtained stable MMNs in adults and children. The amplitude of MMN was largest when durationof the deviant stimulus, stimulation rate and probability of the deviant stimulus were 125 msec, 0.9/sec and 5% respectively.Conclusion：The MMNs can be obtained from healthy adults and cooperative children. The MMN could be used as an objectivemeasure for central auditory processing and individual discrimination ability. (Korean J Otolaryngol 2006;49:1151-8)

#사건관련전위·Mismatch negativity·자극빈도·자극 지속시간·비율. #Event-related potential·Mismatch negativity·Stimulation rate·Duration·Probability.

참고문헌 (19)

참고문헌 신청

/ / Separate representation of stimulus frequency and duration in auditory sensoty memory

/ 1990 / Brain generators implicatedin the processing of auditory stimulus deviance:A topographicevent-related potential study 27 : 627 ~ 40

/ 1991 / Acommemtary on Woldorff et al : 30 ~ 42

/ 1993 / Electrophysiologicalindicator of awakwning from coma 341 : 688 ~

/ 1993 / Mismatch negativityarea and age-related auditory memory 87 : 321 ~ 5

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