지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 168 - 172 (5page)
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초록· 키워드
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Background Multifocal motor neuropathy (MMN) is an immune-mediated disorder that is characterized by slowly progressive and asymmetrical weakness, but its pathophysiological mechanism is uncertain. The hypothesis that MMN is an immunological disease has been supported by the proven therapeutic effects of intravenous immunoglobulin and the detection of antiganglioside antibodies in MMN patients. The coexistence of MMN with other immune diseases has been rarely reported.
Case Report A 37-year-old woman visited our hospital complaining of weakness in both hands. The clinical manifestations coincided well with MMN: predominantly distal upper-limb weakness, asymmetric involvement, a progressive course, absence of sensory symptoms, absence of pyramidal signs, and sparing of the cranial muscles. The electrophysiological findings also supported a diagnosis of MMN, with motor nerve conduction block in the median, ulnar,and radial nerves, without sensory nerve involvement. The patient was simultaneously diagnosed as having Hashimoto’s thyroiditis, which is a well-known immune-mediated disease.
Conclusions The concurrence of MMN and Hashimoto’s thyroiditis in our patient is significant for understanding the immunological characteristics of the two diseases.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Amino N / 2002 / Hashimoto’s disease and Dr. Hakaru Hashimoto / Endocr J 49 : 393 ~ 397
Arasaki K / 1993 / Acute conduction block in vitro following exposure to antiganglioside sera / Muscle Nerve 16 : 587 ~ 593
Chaudhry V / 1994 / Multifocal motor neuropathy: electrodiagnostic features / Muscle Nerve 17 : 198 ~ 205
Fishman PS / 1991 / Antibodies to the ganglioside GD1b in a patient with motor neuron disease and thyroid adenoma / Arch Neurol 48 : 1188 ~ 1190
Jenkins RC / 2002 / Disease associations with autoimmune thyroid disease / Thyroid 12 : 977 ~ 988
Arasaki K / 1993 / Acute conduction block in vitro following exposure to antiganglioside sera / Muscle Nerve 16 : 587 ~ 593
Chaudhry V / 1994 / Multifocal motor neuropathy: electrodiagnostic features / Muscle Nerve 17 : 198 ~ 205
Fishman PS / 1991 / Antibodies to the ganglioside GD1b in a patient with motor neuron disease and thyroid adenoma / Arch Neurol 48 : 1188 ~ 1190
Jenkins RC / 2002 / Disease associations with autoimmune thyroid disease / Thyroid 12 : 977 ~ 988
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