지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2003.1
- 수록면
- 627 - 633 (7page)
이용수
초록· 키워드
오류제보하기
Background and Objectives：The purpose of this study is to find out the exact distribution of nitric oxide synthase (NOS) in the cochlea and vestibular organ of normal guinea pig. Nitric oxide (NO) is synthesized from L-arginine catalyzed by NOS and neurotransmision of the inner ear and the regulation of cochlear blood flow in physiological condition. In addition, exces NO is involved in cytotoxicity. Materials and Method：Five normal guinea pigs were used. Antibodies to thre isoforms of NOS (nNOS, eNOS, iNOS) were utilized to stain the parafin sections of cochlea and vestibular organ (crista and maculae utriculi). Staining patterns were compared to previous reports. Results：Neuronal NOS (nNOS) was constitutively expressed in the lateral cochlear wall (stria vascularis, spiral ligament), spiral ganglion, hair cells and supporting cells in the cochlea. In the vestibular organs, hair cels were well expressed. Endothelial NOS (eNOS) was expresed in the vascular endothelium, cochlear lateral wall, basal parts of hair cells and spiral ganglion in the cochlea. Vascular endothelium and nerve fiber including nerve calyx were also prominently expressed. No inducible NOS (iNOS) was identified in any sections. Conclusion：Neuronal and endothelial NOS were constitutively expresed in the inner ear of normal guinea pig. This distribution can explain the role of (Korean J Otolaryngol 2003 ;46 :627-33)
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
노화가 사람 치은섬유아세포의 nitric oxide와 inducible nitric oxide synthase 발현에 끼치는 영향
Journal of Periodontal & Implant Science
2006 .01
-
Elevation of Nitric Oxide Synthase Activity by Dimethyladenosine from Silkworm Pupae in Aged Rats
Toxicological Research
2008 .09
-
한국인 정신분열병 환자에서 Endothelial Nitric Oxide Synthase 유전자의 다형성
신경정신의학
2004 .01
-
전정기관과 와우의 발생
대한이비인후-두경부외과학회지
2010 .01
-
백서의 경혈(해계, 곤륜, 양보) 침자가 Nitric Oxide Synthase 및 Nitric Oxide의 변화에 미치는 영향
Korean Journal of Acupuncture
2013 .01
-
분리배양된 신생 흰쥐 나선신경절세포의 면역염색학적 특징
대한이비인후-두경부외과학회지
2002 .01
-
Inhibitory effects of new quinone compounds on eNOS activity in rat aorta and nNOS activity in rat brain
대한약학회 학술대회
2002 .01
-
Hypoxia Enhances Nitric Oxide Synthesis by Upregulation of Inducible Nitric Oxide Synthase in Endothelial Cells
대한의생명과학회지
2013 .09
-
Arsenite Acutely Decreases Nitric Oxide Production via the ROS-Protein Phosphatase 1-Endothelial Nitric Oxide Synthase-Thr<sup>497</sup> Signaling Cascade
Biomolecules & Therapeutics(구 응용약물학회지)
2014 .01
-
유방암에서 Nitric Oxide Synthase의 발현
Annals of Surgical Treatment and Research
2002 .08
-
유방암에서 Nitric Oxide Synthase (NOS)의 발현
대한외과학회 학술대회 초록집
2002 .05
-
INCREASED NITRIC OXIDE PRODUCTION MEDIATES ISCHEMIC BRAIN DAMAGE : DIRECT MEASUREMENT OF NITRIC OXIDE AND ENHANCED ACTIVITY OF NITRIC OXIDE SYNTHASE IN BRAIN MICROVESSELS AFTER CEREBRAL ISCHEMIA
한국응용약물학회 춘계학술발표논문집
1995 .01
-
Taurine Activates ERK2 and Induces the Production of Nitric Oxide in Osteoblast-like UMR-106 Cells
한국응용약물학회 추계학술발표논문집
1998 .01
-
Nitric Oxide와 종양
대한내과학회지
2010 .01
-
Therapeutic Application of Nitric Oxide in Human Diseases
Biomolecules & Therapeutics(구 응용약물학회지)
2010 .01
-
백색 기니픽 와우에서 Protein Kinase C 아형의 발현
대한이비인후-두경부외과학회지
2003 .01
-
EFFECTS OF NITRIC OXIDE SYNTHASE INHIBITORS ON OSTEOCLAST-LIKE CELL FORMATION
대한치과교정학회지
1995 .12
-
인간의 갑상선 결절성 과증식증과 유두상 암종에서의 Endothelial Nitric Oxide의 발현
대한 두경부 종양 학술지
2001 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0