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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 384 - 386 (3page)
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Dear Editor, We describe the diagnostic characteristics of three pediatric patients with early T-cell precursor (ETP)-ALL. All three patients had hyperleukocytosis with a white blood cell (WBC) count of more than 100.0×109/L, showed immunophenotypic findings consistent with ETP-ALL, and were positive for FLT3 mutations. The clinical and laboratory findings, including immunophenotyping results (Fig. 1), T-cell receptor (TCR) rearrangements, Fms-related tyrosine kinase 3 (FLT3) mutations, and karyotype results, for the three patients are summarized in Table 1. The aim of this report is to provide information on ETP-ALL and reveal the immunophenotypic and molecular characteristics of ETP-ALL in pediatric patients.
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참고문헌 (10)
참고문헌 신청
Coustan-Smith E / 2009 / Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia / Lancet Oncol 10:147~156
Allen A / 2013 / Early T-cell precursor leukemia/lymphoma in adults and children / Leuk Res 37:1027~1034
Zuurbier L / 2014 / Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors / Haematologica 99:94~102
Borowitz MJ / 2008 / WHO classification of tumours of haematopoietic and lymphoid tissues / IARC :176~178
Rothenberg EV / 2008 / Launching the T-cell-lineage developmental programme / Nat Rev Immunol 8:9~21
Allen A / 2013 / Early T-cell precursor leukemia/lymphoma in adults and children / Leuk Res 37:1027~1034
Zuurbier L / 2014 / Immature MEF2C-dysregulated T-cell leukemia patients have an early T-cell precursor acute lymphoblastic leukemia gene signature and typically have non-rearranged T-cell receptors / Haematologica 99:94~102
Borowitz MJ / 2008 / WHO classification of tumours of haematopoietic and lymphoid tissues / IARC :176~178
Rothenberg EV / 2008 / Launching the T-cell-lineage developmental programme / Nat Rev Immunol 8:9~21
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