지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 371 - 380 (10page)
이용수
초록· 키워드
오류제보하기
Background: We aimed to assess the performance of the five creatinine-based equations commonly used for estimates of the glomerular filtration rate (eGFR), namely, the creatinine-based Chronic Kidney Disease Epidemiology Collaboration (CKD-EPIcr), Asian CKD-EPI, revised Lund–Malmö (revised LM), full age spectrum (FAS), and Korean FAS equations, in the Korean population.
Methods: A total of 1,312 patients, aged 20 yr and above who underwent 51Cr-EDTA GFR measurements (mGFR), were enrolled. The bias (eGFR–mGFR) and precision (root mean square error [RMSE]) were calculated. The accuracy (P30) of four eGFR equations was compared to that of the CKD-EPIcr equation. P30 was defined as the percentage of patients whose eGFR was within±30% of the mGFR.
Results: The mean bias (mL·min-1·1.73 m-2) of the five eGFR equation was as follows: CKD-EPIcr, –0.6; Asian CKD-EPI, 2.7; revised LM, –6.5; FAS, –2.5; and Korean FAS, –0.2. The bias of the Asian CKD-EPI, revised LM, and FAS equations showed a significant difference from zero (P<0.001). The RMSE values were as follows: CKD-EPIcr, 15.6; Asian CKD-EPI, 15.6; revised LM, 17.9; FAS, 16.3; and Korean FAS, 15.8. There were no significant differences in the P30 except for the Asian CKD-EPI equation: CKD-EPIcr, 76.6%; Asian CKD-EPI, 74.7%; revised LM, 75.8%; FAS, 76.0%; and Korean FAS, 75.8%.
Conclusions: The CKD-EPIcr and Korean FAS equations showed equivalent analytical and clinical performances in the Korean adult population.
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Bjork J / 2011 / Revised equations for estimating glomerular filtration rate based on the Lund-Malmo Study cohort / Scand J Clin Lab Invest 71 : 232 ~ 239
Bjork J / 2015 / Accuracy of GFR estimating equations combining standardized cystatin C and creatinine assays: a cross-sectional study in Sweden / Clin Chem Lab Med 53 : 403
Bjork J / 2015 / Performance of GFR estimating equations stratified by measured or estimated GFR: Implications for interpretation / Am J Kidney Dis 66 : 1107 ~ 1108
CLSI / 2008 / Defining, establishing, and verifying reference intervals in the clinical laboratory. Approved Guideline-Third Edition. CLSI document EP28-A3c / Clinical and Laboratory
Delanaye P / 2011 / Estimating glomerular filtration rate in Asian subjects: where do we stand? / Kidney Int 80 : 439 ~ 440
Bjork J / 2015 / Accuracy of GFR estimating equations combining standardized cystatin C and creatinine assays: a cross-sectional study in Sweden / Clin Chem Lab Med 53 : 403
Bjork J / 2015 / Performance of GFR estimating equations stratified by measured or estimated GFR: Implications for interpretation / Am J Kidney Dis 66 : 1107 ~ 1108
CLSI / 2008 / Defining, establishing, and verifying reference intervals in the clinical laboratory. Approved Guideline-Third Edition. CLSI document EP28-A3c / Clinical and Laboratory
Delanaye P / 2011 / Estimating glomerular filtration rate in Asian subjects: where do we stand? / Kidney Int 80 : 439 ~ 440
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