지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한노인병학회 Annals of geriatric medicine and research Annals of geriatric medicine and research Vol.21 No.1
- 발행연도
- 2017.1
- 수록면
- 10 - 16 (7page)
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Background: The aim of this study was to investigate the predictive value of estimated glomerular filtration rate (eGFR) calculated with the simplified Modification of Diet in Renal Disease (MDRD) Study and Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations for prognosis in elderly patients with acute myocardial infarction (AMI). Methods: This study included 1,372 patients (mean age, 64.2±11.8 years; men, 67.9%) entered in the Kyungpook National University Hospital Acute Myocardial Infarction Registry from November 2005 to February 2010. We analyzed 1-year major adverse cardiac events (MACE) according to the eGFR calculated with the simplified MDRD Study and CKD-EPI equations. Results: The mean eGFR values calculated with the MDRD Study and CKD-EPI equations were 81.3±44.4 and 78.5±27.1 mL/(min/1.73 m2), respectively. In receiver operating characteristic curve analysis for prediction of 1-year MACE, the area under the curve based on the CKD-EPI equation was greater than that using the MDRD Study equation (CKD-EPI equation vs. MDRD Study equation: 0.691 vs. 0.674, p=0.041). Multivariate analysis using a Cox proportional hazards model revealed that the eGFR calculated with the CKD-EPI equation was an independent predictor of the occurrence of MACE within 1 year after AMI. However, eGFR calculated with the MDRD Study equation did not have predictive value. Furthermore, the eGFR calculated with the CKD-EPI equation had incremental prognostic value for established risk factors (chi-square=5.78, p=0.016). Conclusion: The eGFR calculated using the CKD-EPI equation was an independent predictor of 1-year MACE in elderly patients with AMI.
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참고문헌 (24)
참고문헌 신청
김동희 / 2013 / 노인 흉통 환자의 임상적 특징: 관상동맥 조영술 시행 노인 환자를 대상으로 한 관찰 연구 / Annals of geriatric medicine and research 17(1):37~40
Anavekar NS / 2004 / Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction / N Engl J Med 351:1285~1295
Al Suwaidi J / 2002 / Prognostic implications of abnormalities in renal function in patients with acute coronary syndromes / Circulation 106:974~980
Sarnak MJ / 2003 / Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention / Circulation 108:2154~2169
Levey AS / 1999 / A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation / Ann Intern Med 130:461~470
Anavekar NS / 2004 / Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction / N Engl J Med 351:1285~1295
Al Suwaidi J / 2002 / Prognostic implications of abnormalities in renal function in patients with acute coronary syndromes / Circulation 106:974~980
Sarnak MJ / 2003 / Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Prevention / Circulation 108:2154~2169
Levey AS / 1999 / A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation / Ann Intern Med 130:461~470
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