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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 523 - 530 (8page)
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초록· 키워드
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We compared the activities of tedizolid to those of linezolid and other commonly used antimicrobial agents against gram-positive cocci recovered from patients with skin and skin structure infections (SSSIs) and hospital-acquired pneumonia (HAP) in Korean hospitals. Gram-positive isolates were collected from 356 patients with SSSIs and 144 patients with HAP at eight hospitals in Korea from 2011 to 2014. SSSIs included impetigo, cellulitis, erysipelas, furuncles, abscesses, and infected burns. Antimicrobial susceptibility was tested by using the CLSI agar dilution method. All of the gram-positive isolates were inhibited by ≤1 μg/mL tedizolid. The minimum inhibitory concentration [MIC]90 of tedizolid was 0.5 μg/mL for methicillin-resistant Staphylococcus aureus, which was 4-fold lower than that of linezolid. Tedizolid may become a useful option for the treatment of SSSIs and HAP caused by gram-positive bacteria.
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등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
/ 2014 / Sivextro (tedizolid) Prescribing information / Cubist Pharmaceuticals
Brook I / 2013 / Antianaerobic antimicrobials: spectrum and susceptibility testing / Clin Microbiol Rev 26 : 526 ~ 546
Goldstein EJ / 2011 / Clinical efficacy and correlation of clinical outcomes with in vitro susceptibility for anaerobic bacteria in patients with complicated intra-abdominal
Gu B / 2013 / The emerging problem of linezolid-resistant Staphylococcus / J Antimicrob Chemother 68 : 4 ~ 11
Kisgen JJ / 2014 / Tedizolid: a new oxazolidinone antimicrobial / Am J Health Syst Pharm 71 : 621 ~ 633
Brook I / 2013 / Antianaerobic antimicrobials: spectrum and susceptibility testing / Clin Microbiol Rev 26 : 526 ~ 546
Goldstein EJ / 2011 / Clinical efficacy and correlation of clinical outcomes with in vitro susceptibility for anaerobic bacteria in patients with complicated intra-abdominal
Gu B / 2013 / The emerging problem of linezolid-resistant Staphylococcus / J Antimicrob Chemother 68 : 4 ~ 11
Kisgen JJ / 2014 / Tedizolid: a new oxazolidinone antimicrobial / Am J Health Syst Pharm 71 : 621 ~ 633
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