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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 373 - 380 (8page)
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초록· 키워드
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Background : Few studies have evaluated the performance of the recently introduced MicroScan Synergies plus Positive Combo 3 Panels (SIPC3) (Dade Behring Inc., USA). We evaluated the clinical efficacy of the panels in identification (ID) and antimicrobial susceptibility testing (AST) of Staphylococcus aureus and enterococci.
Methods : To evaluate the panels’ accuracy of identification, the results obtained using the test panels were compared with those obtained by using conventional biochemical tests in conjunction with VITEK 2 system (bio-Merieux, USA). In addition, the AST results obtained using the panels were compared with those obtained by performing CLSI broth microdilution.
Results : The overall agreement between the approaches for the ID of S. aureus and enterococci was 100% and 96%, respectively. The categorical and essential agreements (CA and EA) for S. aureus were 98%, each. Very major errors (VME), major errors (ME), and minor error (mE) for S. aureus were 0.45%, 0.3%, and 4.2%, respectively. The majority of VMEs were for oxacillin (8.6%), penicillin (2.0%), erythromycin (7.9%), clindamycin (3.8%), and tetracycline (4.1%). For enterococci, the CA, EA, VME,ME, and mE were 88.8%, 93.7%, 4.4%, 0%, and 2.8%, respectively. The 80.5% (29/36) of Enterococcus faecium had concordant ID with the reference. Most of the categorical errors (3 VMEs and 14 mEs) were observed for quinupristin/dalfopristin (Synercid; Catalytica Pharmaceuticals Inc., USA).
Conclusions : The panels compared favorably with conventional methods for the ID and AST of S. aureus. However, we expected a better performance for ID of E. faecium and AST using Synercid. (Korean J Lab Med 2010;30:373-80)
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참고문헌 (22)
참고문헌 신청
Clinical and Laboratory Standards Institute / 2006 / Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically:approved standard. CLSI document M07-A7.
Clinical and Laboratory Standards Institute / 2006 / Performance standards for antimicrobial disk susceptibility tests: approved standard. CLSI document M02-A9. 9th ed / CLSI
Eigner U / 2005 / Analysis of the comparative workflow and performance characteristics of the VITEK 2 and Phoenix systems / J Clin Microbiol 43 : 3829 ~ 3834
Felten A / 2002 / Evaluation of three techniques for detection of low-level methicillin-resistant Staphylococcus aureus (MRSA): a disk diffusion method with cefoxitin and mo
Ito T / 1998 / Acquisition of methicillin resistance and progression of multiantibiotic resistance in methicillin-resistant Staphylococcus aureus / Yonsei Med J 39 : 526 ~ 53
Clinical and Laboratory Standards Institute / 2006 / Performance standards for antimicrobial disk susceptibility tests: approved standard. CLSI document M02-A9. 9th ed / CLSI
Eigner U / 2005 / Analysis of the comparative workflow and performance characteristics of the VITEK 2 and Phoenix systems / J Clin Microbiol 43 : 3829 ~ 3834
Felten A / 2002 / Evaluation of three techniques for detection of low-level methicillin-resistant Staphylococcus aureus (MRSA): a disk diffusion method with cefoxitin and mo
Ito T / 1998 / Acquisition of methicillin resistance and progression of multiantibiotic resistance in methicillin-resistant Staphylococcus aureus / Yonsei Med J 39 : 526 ~ 53
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