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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 420 - 424 (5page)
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Background: The urinary albumin/creatinine ratio (ACR) is an important indicator of albuminuria. We aimed to estimate ACR uncertainty and its impact on test results and proposed imprecision quality goals based on the estimated uncertainty. Methods: The combined ACR uncertainty was calculated using the individual uncertainties of urinary albumin and creatinine. ACR confidence intervals (CIs) were estimated based on the expanded uncertainty. When the CI contained the ACR category boundary (30 or 300 mg/g), the cases were considered ambiguous. Quality goals for ACR were suggested using the number of ambiguous cases among actual patient results. Results: The number of ambiguous cases resulting from the combined ACR uncertainty was higher than expected based on biological variation (BV) quality goals. When the ACR met BV quality specifications, we estimated that 4.8–15.5% of the results may have been misclassified. To minimize the number of ambiguous results, the minimum, desirable, and optimum quality goals were set at 34.0%, 18.0%, and 4.5%, respectively. Conclusions: We expressed ACR uncertainty using the uncertainties of urinary albumin and creatinine and assessed the impact of this combined uncertainty on the test results. Subsequently, we proposed imprecision quality goals for ACR based on ambiguous results.
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등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Lambers Heerspink HJ / 2015 / Albuminuria is an appropriate therapeutic target in patients with CKD: the Pro View / Clin J Am Soc Nephrol 10:1079~1088
Currie G / 2013 / Proteinuria and its relation to cardiovascular disease / Int J Nephrol Renovasc Dis 7:13~24
Rodby RA / 2016 / Timed urine collections for albumin and protein: "The King Is Dead, Long Live the King!" / Am J Kidney Dis 68:836~838
Talreja H / 2014 / Predicting kidney transplantation outcomes using proteinuria ascertained from spot urine samples versus timed urine collections / Am J Kidney Dis 64:962~968
American Diabetes Association / 2017 / Standards of medical care in diabetes-2017: summary of revisions / Diabetes Care 40(S1):S4~S5
Currie G / 2013 / Proteinuria and its relation to cardiovascular disease / Int J Nephrol Renovasc Dis 7:13~24
Rodby RA / 2016 / Timed urine collections for albumin and protein: "The King Is Dead, Long Live the King!" / Am J Kidney Dis 68:836~838
Talreja H / 2014 / Predicting kidney transplantation outcomes using proteinuria ascertained from spot urine samples versus timed urine collections / Am J Kidney Dis 64:962~968
American Diabetes Association / 2017 / Standards of medical care in diabetes-2017: summary of revisions / Diabetes Care 40(S1):S4~S5
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