지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2010.1
- 수록면
- 325 - 328 (4page)
이용수
초록· 키워드
오류제보하기
The human apolipoprotein E (APOE) gene contains several single-nucleotide polymorphisms (SNPs) that are distributed across the gene. The genotype of the APOE gene has important implications as a risk factor for various diseases. We observed 2 cases in which the results of allele-specific PCR (AS-PCR) of the APOE gene were not consistent with those of fluorescence resonance energy transfer (FRET) or sequencing analysis. In these cases, genotyping by AS-PCR showed that patients were ε2 homozygotes, while sequencing analysis and FRET showed that they were ε2/ε3 heterozygotes. Herein, we describe the causes of the errors in genotyping and describe the significance of these errors. (Korean J Lab Med 2010;30:325-8)
목차
등록된 정보가 없습니다.
참고문헌 (13)
참고문헌 신청
Ballerini S / 2002 / Apolipoprotein E genotyping: a comparative study between restriction endonuclease mapping and allelic discrimination with the LightCycler / Clin Chim Act
Corder EH / 1993 / Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families / Science 261 : 921 ~ 923
Dong J / 2000 / Human apolipoprotein E7:lysine mutations in the carboxy-terminal domain are directly responsible for preferential binding to very low density lipoproteins /
Donohoe GG / 1999 / Rapid identification of apolipoprotein E genotypes by multiplex amplification refractory mutation system PCR and capillary gel electrophoresis / Clin Chem
Gomez-Isla T / 1996 / Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer’s disease / Ann Neurol 39 : 62 ~ 70
Corder EH / 1993 / Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer’s disease in late onset families / Science 261 : 921 ~ 923
Dong J / 2000 / Human apolipoprotein E7:lysine mutations in the carboxy-terminal domain are directly responsible for preferential binding to very low density lipoproteins /
Donohoe GG / 1999 / Rapid identification of apolipoprotein E genotypes by multiplex amplification refractory mutation system PCR and capillary gel electrophoresis / Clin Chem
Gomez-Isla T / 1996 / Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer’s disease / Ann Neurol 39 : 62 ~ 70
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Apolipoprotein E Genotype and Expression Correlated with Hepatitis C Virus Genotype and Infection
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2019 .03
-
Association between apolipoprotein E genotype, chronic liver disease, and hepatitis B virus
Clinical and Molecular Hepatology
2012 .01
-
Association between Apolipoprotein E Polymorphism and Chronic Kidney Disease in the Korean General Population: Dong-gu Study
Korean Journal of Family Medicine
2014 .01
-
건강한 여성 근로자에서 Apolipoprotein E와 혈중 지질 농도와의 관련성
예방의학회지
2010 .01
-
Apolipoprotein E (APOE) Polymorphisms and Susceptibility to Breast Cancer: A Meta-Analysis
Cancer Research and Treatment
2012 .01
-
아포지단백 E 유전자 다형성 분석법의 비교: INNO-LiPA ApoE Kit, AllelicDiscrimination with LightCycler 및 BioCore ApoE Kit
Annals of Laboratory Medicine
2004 .01
-
뇌혈관 협착을 가진 환자에서 아포지단백질 E의 유전형과 대뇌 소혈관 질환과의 연관성
대한뇌졸중학회지
2008 .01
-
노인인구에서 ApoE 유전자형에 따른 머리둘레와 인지기능간의 연관성
신경정신의학
2007 .01
-
노인 인지 기능에 기여하는 유전적, 신경심리학적 요인 분석: APOE유전형과 연령의 상호작용 분석
Annals of Laboratory Medicine
2002 .01
-
ApoE Polymorphism May Determine Low-Density Lipoprotein Cholesterol Level in Association with Obesity and Metabolic Syndrome in Postmenopausal Korean Women
Yonsei Medical Journal
2011 .01
-
Gene-gene interaction in cerebral infarction patients: Relationship between apolipopreotein E gene polymorphism and Sasang-constitution
Oriental pharmacy and experimental medicine
2004 .01
-
Association among apolipoprotein E gene polymorphism, diabetes mellitus, and ischemic cerebrovascular disease in Koreans
Oriental pharmacy and experimental medicine
2006 .01
-
폐암 억제유전자 RRM1의 단일염기다형성 검사를 위한 PCR-RFLP법과 Real-Time PCR법의 유용성 비교
Tuberculosis and Respiratory Diseases
2007 .01
-
만성 C형 간염에서 아포지단백E 유전자형과 치료반응과의 관련성
Annals of Clinical Microbiology
2013 .01
-
Association of Apolipoprotein E Polymorphisms with White Matter Lesions and Brain Atrophy
PSYCHIATRY INVESTIGATION
2020 .01
-
Improved Polymerase Chain Reaction Method for Genotyping Lepob Mouse Using Mismatched Allele-Specific Primers
Laboratory Animal Research
2009 .12
-
196G/A of the Brain-Derived Neurotrophic Factor Gene Polymorphisms Predicts Suicidal Behavior in Schizophrenia Patients
PSYCHIATRY INVESTIGATION
2018 .01
-
The Study of Synergy between the BchE-k Variant and the ApoE Gene in the Alzheimer Dementia of the Korean Population
Journal of genetic medicine
1999 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0