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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 413 - 416 (4page)
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초록· 키워드
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Although delusion of theft (DT) is the most frequent type of delusion in Alzheimer’s disease (AD), its relationship to cognitive functions remains unclear. The aim of this study was to demonstrate the relationship between DT and cognitive functions in mild AD. Two hundred eighty-nine mild AD patients were enrolled in this study. These subjects were classified into three groups: patients with no delusions (ND, n=82), patients with paranoid delusions (PD, n=114) and patients with DT (n=93). Cognitive functions and their associations with the degree of delusion were compared among the three groups. The results showed that verbal Fluency scores were significantly lower in the PD group than in the DT and ND groups. Word List Recall scores were significantly lower in the DT group than in the PD and ND groups. Interestingly, delusion severity measured with the Neuropsychiatric Inventory delusion subscale correlated negatively with the Word List Recall scores in the DT group. In this study, we demonstrated that episodic memory functions in mild AD patients were associated with DT, but not with PD. Further studies might be needed to clarify the pathophysiology of delusions associated with AD.
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등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Cipriani G / 2014 / Understanding delusion in dementia: a review / Geriatr Gerontol Int 14:32~39
Ornstein K / 2013 / The differential impact of unique behavioral and psychological symptoms for the dementia caregiver: how and why do patients' individual symptom clusters impact caregiver depressive symptoms? / Am J Geriatr Psychiatry 21:1277~1286
Apostolova LG / 2014 / Risk factors for behavioral abnormalities in mild cognitive impairment and mild Alzheimer's disease / Dement Geriatr Cogn Disord 37:315~326
Zhao Q-F / 2016 / The prevalence of neuropsychiatric symptoms in Alzheimer's disease: systematic review and meta-analysis / J Affect Disord 190:264~271
Holt AE / 2006 / Cognitive neuroscience of delusions in aging / Neuropsychiatr Dis Treat 2:181~189
Ornstein K / 2013 / The differential impact of unique behavioral and psychological symptoms for the dementia caregiver: how and why do patients' individual symptom clusters impact caregiver depressive symptoms? / Am J Geriatr Psychiatry 21:1277~1286
Apostolova LG / 2014 / Risk factors for behavioral abnormalities in mild cognitive impairment and mild Alzheimer's disease / Dement Geriatr Cogn Disord 37:315~326
Zhao Q-F / 2016 / The prevalence of neuropsychiatric symptoms in Alzheimer's disease: systematic review and meta-analysis / J Affect Disord 190:264~271
Holt AE / 2006 / Cognitive neuroscience of delusions in aging / Neuropsychiatr Dis Treat 2:181~189
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