지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 454 - 463 (10page)
이용수
초록· 키워드
오류제보하기
Background and Purpose Several studies have validated the clinical efficacy of computerized cognitive training applications. However, few studies have investigated the neural substrates of these training applications using simultaneous multimodal neuroimaging modalities. We aimed to determine the effectiveness of computerized cognitive training and corresponding neural substrates through a multimodal approach. Methods Ten patients with mild cognitive impairment (MCI), six patients with subjective memory impairment (SMI), and 10 normal controls received custom-developed computerized cognitive training in the memory clinic of a university hospital. All of the participants completed 24 sessions of computerized cognitive training, each lasting 40 minutes and performed twice weekly. They were assessed using neuropsychological tests (both computerized and conventional), electroencephalography, fluorodeoxyglucose positron-emission tomography (FDGPET), volumetric magnetic resonance imaging (MRI), and diffusion-tensor imaging (DTI) at pre- and posttraining. Results The patients with MCI exhibited significant improvements in the trail-making test– black & white-B, and memory domain of the computerized cognitive assessment. Subjects with normal cognition exhibited significant improvements in scores in the language and attention-/ psychomotor-speed domains. There were no significant changes in subjects with SMI. In the pre- and posttraining evaluations of the MCI group, FDG-PET showed focal activation in the left anterior insula and anterior cingulate after training. Volumetric MRI showed a focal increase in the cortical thickness in the rostral anterior cingulate. DTI revealed increased fractional anisotropy in several regions, including the anterior cingulate. Conclusions The anterior cingulate and anterior insula, which are parts of the salience network, may be substrates for the improvements in cognitive function induced by computerized cognitive training.
목차
등록된 정보가 없습니다.
참고문헌 (4)
참고문헌 신청
Dale AM / 1999 / Cortical surface-based analysis. I. segmentation and surface reconstruction / NeuroImage 9:179~194
Jenkinson M / 2012 / FSL / NeuroImage 62:782~790
Smith SM / 2006 / Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data / NeuroImage 31:1487~1505
Nichols TE / 2002 / Nonparametric permutation tests for functional neuroimaging: a primer with examples / Hum Brain Mapp 15:1~25
Jenkinson M / 2012 / FSL / NeuroImage 62:782~790
Smith SM / 2006 / Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data / NeuroImage 31:1487~1505
Nichols TE / 2002 / Nonparametric permutation tests for functional neuroimaging: a primer with examples / Hum Brain Mapp 15:1~25
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Low Anterior Resection Syndrome
대한외과학회 학술대회 초록집
2021 .11
-
The association of the caudate and cingulate cortex connectivity with executive function in children and adolescents according to age
대한소아청소년정신의학회 학술대회논문집
2022 .11
-
Surgery for subaxial cervical spine injuries: which is better: anterior, posterior, or anterior–posterior combined approach?: a systematic review and meta-analysis
Asian Spine Journal
2024 .08
-
Gray Matter Microstructural Abnormalities and Working Memory Deficits in Individuals with Schizophrenia
PSYCHIATRY INVESTIGATION
2019 .01
-
The Relationships between Anterior Chamber Parameters and Obesity
Korean Journal of Ophthalmology
2015 .01
-
Comparison of clinical outcomes for arthroscopic anterior labral repair surgery between shoulder anterior microinstability and classic anterior shoulder instability
대한견주관절의학회 학술대회논문집
2021 .03
-
How-I-Do-It: Practical Tips for Anterior Approach (Video)
대한외과학회 학술대회 초록집
2018 .11
-
Whole Brain Voxel-Wise Analysis of Cerebral Retention of Beta-Amyloid in Cognitively Normal Older Adults Using 18F-Florbetaben
PSYCHIATRY INVESTIGATION
2017 .01
-
연령, 성별, 머리 크기가 대뇌 피질 두께에 미치는 효과
생물정신의학
2015 .01
-
Abnormal Responses in Cognitive Impulsivity Circuits Are Associated with Glycosylated Hemoglobin Trajectories in Type 1 Diabetes Mellitus and Impaired Metabolic Control
Diabetes and Metabolism Journal
2022 .11
-
Altered Functional Connectivity of the Default Mode Network in Low-Empathy Subjects
Yonsei Medical Journal
2017 .01
-
Neurodevelopmental Changes in Social Reinforcement Processing: A Functional Magnetic Resonance Imaging Study
Clinical Psychopharmacology and Neuroscience
2017 .01
-
Translucency Parameter of Anterior Implant Site
대한치과재료학회 학술대회
2018 .11
-
Flow recovery after posterior clinoidectomy for surgical clipping of anterior choroidal aneurysm
Journal of Cerebrovascular and Endovascular Neurosurgery
2021 .12
-
Comparison Between 18F-Florapronol and 18F-Florbetaben Imaging in Patients With Cognitive Impairment
Journal of Clinical Neurology
2023 .05
-
Screening for variations in anterior digastric musculature prior to correction of post-traumatic anterior open bite by injection of botulinum toxin type A: a technical note
대한구강악안면외과학회지
2015 .01
-
제1형 양극성장애 환자에서 대뇌피질 주름 패턴의 변형 : Local Gyrification Index 분석
생물정신의학
2017 .01
-
Understanding of the anatomy for nerve blocks of anterior abdominal wall
대한외과학회 학술대회 초록집
2015 .11
-
The Comparison for Serratus Anterior Muscle Activity during Protraction in Open Chain and Closed Chain Exercises in Healthy Adults
근골격계과학기술학회
2018 .06
-
Clinical outcome and arthroscopic findings of anterior shoulder stabilization in patients older than 40 years
대한견주관절의학회 학술대회논문집
2015 .04
이 논문의 저자 정보
최근 본 자료
댓글(0)
0